PPP2R5D Variants in Patients Diagnosed With Parkinson’s Disease. A Large‑Scale Multi‑Cohort Analysis
Objective: To identify individuals with rare pathogenic and potentially pathogenic variants of unknown significance (VUS) in PPP2R5D within large Parkinson’s disease (PD) cohorts, to characterize…Should we really forget DBS in Parkinson’s Patients with Dementia?
Objective: To determine whether DBS is really an absolute contraindication in patients with Parkinson’s dementia. Background: It is well established in the literature that Parkinson’s…From Roots to Relief: A Systematic Review of Herbal Medicines in Parkinson’s Management
Objective: To systematically review clinical evidence on herbal medicines for Parkinson’s disease (PD), focusing on motor and non-motor symptoms (NMS). Background: Levodopa remains the standard…Complete Resolution of Troublesome Dyskinesia in People With Advanced Parkinson’s Disease Treated With Foslevodopa/Foscarbidopa: Post Hoc Analysis From a 52-Week Phase 3 Trial
Objective: To evaluate the achievement of complete elimination of troublesome dyskinesia (TSD) and associated changes in Off time, motor aspects of experiences of daily living…Subregional Striatal Dopaminergic Deficits, Cerebral Hypoperfusion and Cognitive Impairment in Parkinson’s Disease
Objective: To investigate the associations of subregional striatal dopaminergic deficits with regional cerebral blood flow (CBF) and cognitive impairment in patients with Parkinson’s disease (PD).…Effects of Modafinil on Motor and Non‑Motor Outcomes in Parkinson’s Disease: A Meta‑Analysis of Randomized, Placebo‑Controlled Trials
Objective: To determine the efficacy and safety of modafinil on motor and non-motor outcomes in Parkinson’s disease (PD) using evidence exclusively from randomized placebo‑controlled clinical…Multimodal Deep Learning for Parkinson’s Disease Screening: Fusing Quantitative Gait Analysis and Clinical Features
Objective: To develop and validate a machine learning model integrating quantitative gait parameters and clinical features to enhance the diagnostic accuracy of Parkinson's disease (PD)…Functional neurosurgery in Parkinson’s disease: Effects on quality of life.
Objective: This study aims to determine the impact of surgical procedures on quality of life in patients with PD using the PDQ-39 questionnaire. Background: Parkinson's…Strengthening Global Parkinson’s Disease Research Capacity through the GP2 ‘Train the Trainer’ Framework
Objective: To implement a sustainable ‘Train the Trainer’ model to strengthen research capacity in Parkinson’s disease (PD) genetics across underrepresented regions (URPs). This initiative promotes…Metabolic Syndrome and Disease Severity in Parkinson’s Disease: Association With Clinical Phenotype and Cerebral Small Vessel Disease
Objective: To evaluate the association between Parkinson’s disease (PD) severity (Hoehn & Yahr, H&Y; mild–moderate–severe) and metabolic syndrome (MetS) defined separately by NCEP-ATP III and…
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