Real-World Clinical Outcomes of Adaptive versus Continuous Deep Brain Stimulation in Early-Stage Parkinson’s Disease: A Systematic Review and Meta-Analysis of 2024-2025 Trials
Objective: To evaluate the comparative efficacy, safety, and energy efficiency of adaptive deep brain stimulation (aDBS) versus continuous deep brain stimulation (cDBS) in Parkinson’s disease…Effects of Dance for Parkinson’s on Disease Severity, Functional Mobility, and Habitual Physical Activity: A Feasibility Study
Objective: To examine the feasibility and effects of a Dance for Parkinson’s Disease® (DfPD®) intervention on disease severity, functional mobility, fine manual dexterity, and habitual…Clinical Outcomes and Safety of Ablative Surgery for Parkinson’s Disease in Resource-Limited Settings: A Cohort from Indonesia
Objective: To evaluate the clinical outcomes and safety of ablative surgery for Parkinson’s disease at Indonesia’s national tertiary referral neurological center. Background: Deep brain stimulation…Considering Oral Health to Optimise the Potential for Current and Future Treatments in Parkinson’s Disease
Objective: To determine if the Oral Health Assessment Questionnaire (OHAQ) devised by 2 Parkinson’s Disease Nurse Advanced Practitioners (PDNAP) could facilitate a healthier mouth to…Serum Based biomarkers in Parkinson’s disease with and without cognitive deficits.
Objective: To examine levels of putative biomarker proteins viz., neuronal pentraxin receptor (NPTXR), carnosine dipeptidase-1 (CNDP1), dickkopf-3 (DKK3) in the serum of Parkinson’s Disease patients…Dentate Glutamate as an OFF-State Biomarker of Levodopa-Resistant Postural Tremor in Parkinson’s Disease
Objective: This study aims to ascertain whether OFF-state dentate nucleus glutamate, measured using J-difference edited MRS, predicts residual postural tremor following levodopa in Parkinson’s disease…3D Markerless Video-Based Assessment of Lower Extremity Dystonia in X-linked Dystonia Parkinsonism and DYT-TOR1A
Objective: To evaluate whether markerless video analysis can extract quantitative motor features that reflect dystonia severity in X-linked dystonia parkinsonism (XDP). Background: XDP is an…A Retrospective Comparison of Multiple Approaches to LFP-guided and Imaging Guided Contact Selection in Subthalamic Deep Brain Stimulation for Parkinson’s Disease
Objective: To retrospectively compare several local field potential (LFP)-guided approaches for contact selection with an imaging-guided strategy and monopolar reviews, using long-term motor outcome as…Seronegative Autoimmune Encephalitis Presenting as Hemichorea: A Case Report
Objective: To report a case of hemichorea due to seronegative autoimmune process. Background: Autoimmune encephalitis can present with diverse hyperkinetic or hypokinetic phenomenology. Autoimmune movement…The ORCHESTRA Study Year 2: Practical Experiences With Foslevodopa/Foscarbidopa Treatment in Advanced Parkinson’s Disease in a Real-World Setting
Objective: To describe real-world learnings on the routine practical management of foslevodopa/foscarbidopa (LDp/CDp), a continuous 24-hour subcutaneous infusion therapy for advanced Parkinson’s disease (aPD), using…
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