Continued Evaluation of Clinical Outcomes in Participants With Parkinson’s Disease Through 4 Years After Bemdaneprocel Administration
Objective: To report safety and clinical outcomes in participants with Parkinson’s disease (PD), 4 years after receiving bemdaneprocel. Background: Bemdaneprocel is an investigational cell therapy…Insights on the Groaning Phenomenon from a Large Asian Progressive Supranuclear Palsy Cohort
Objective: We investigated the frequency and phenomenology of groaning in progressive supranuclear palsy (PSP), and its association with disease parameters and caregiver burden. Background: “Purposeless”…Differential Cholinergic White Matter Microstructural Alterations in Multiple System Atrophy and Parkinson’s Disease
Objective: To investigate the extent and pattern of microstructural alterations of cholinergic pathways in MSA and PD. Background: MSA and PD are both α-synucleinopathies with…Midbrain Hypometabolism in Idiopathic REM Sleep Behavior Disorder Detected by [18F]-FDG PET as a Potential Biomarker of Nigral degeneration
Objective: The aim of this study was to investigate whether midbrain hypometabolism can already be detected in iRBD patients using [18F]-FDG PET scans. Background: Parkinson’s…Identifying Informative Speech Tasks for Detecting Clinically Relevant Changes in Parkinson’s Disease
Objective: To identify the most informative speech tasks for detecting clinically relevant speech changes in Parkinson’s Disease (PD) and to develop a streamlined, data-driven assessment…Wearable Gait Metrics as Potential Digital Biomarkers in GBA1 Non-Manifesting Carriers
Objective: To investigate whether sensor–derived gait metrics can detect prodromal motor features in at-risk individuals and evaluate their potential as digital biomarkers for risk stratification.…How Parkinson’s Disease Research Has Shifted from 2016 – 2025 at the MDS Congress: A Topic-Based Analysis
Objective: Characterize temporal changes in PD research priorities presented at the MDS Congress from 2016 to 2025. Identify evolving thematic, methodological, and aging-related directions relevant…Assessing Concordance Between Clinical judgment And 5-2-1 Criteria In Advanced Parkinsons Disease
Objective: 1. Assess how accurately clinicians diagnose Advanced Parkinson’s Disease (APD) in a routine clinical setting2. Evaluate concordance between 5-2-1 criteria and clinician judgement, including…Data Driven Clinical Insights from Longitudinal Cloud-Aggregated Neural Data to Inform a Real-World Adaptive DBS Programming
Objective: Characterize clinical workflow insights gained from expanded access to neural data via a cloud connected platform in adaptive DBS. Background: Adaptive deep brain stimulation…Defining a Population-Based Cohort of Individuals with Probable REM Sleep Behavior Disorder
Objective: To identify a large population-based probable REM sleep behavior disorder (pRBD) cohort of women who are at risk of phenoconversion to Parkinson’s disease (PD)…
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