Low-Intensity Treadmill Training Preserves Motor Function and Muscle Mass Through Mitochondrial and Antioxidant Regulation in a Rat Model of Parkinson’s Disease
Objective: To identify an exercise regimen with the greatest neuroprotective benefit in Parkinson’s disease (PD) and determine whether low-intensity treadmill training preserves motor function and…A Rare Case of PLA2G6 Gene Related Early-Onset Dystonia-Parkinsonism; What Not to Miss Clinically and Radiologically
Objective: PLA2G6-associated neurodegeneration (PLAN) is a rare form of neurodegeneration with brain iron accumulation (NBIA) leading to heterogeneous clinical manifestation including infantile neuroaxonal dystrophy, atypical…Prevalence of drooling in Parkinson’s disease: a multi-center observational study
Objective: This study investigated the prevalence of drooling and related factors. Background: The prevalence of drooling in Parkinson's disease (PD) varies widely, from 10% to…Establishing the Ukrainian Parkinson’s Disease Cohort within GP2: Early Results from the UPGRADE-PD Initiative
Objective: To describe the early establishment and recruitment outcomes of the Ukrainian Parkinson’s disease cohort within the Global Parkinson’s Genetics Program (GP2). Background: Eastern European…Real-World Mobility Measures Reveal Early Indicators of Parkinson’s Disease Risk in Older Women
Objective: To evaluate cost-effective, interpretable methods for identifying elevated risk for Parkinson’s disease using real-world wearable accelerometry and self-reported health data. Background: Mobility changes may emerge…Comprehensive large-scale analysis of gene-environment interactions in Parkinson’s disease
Objective: This study aims to comprehensively explore the gene-environment interactions in PD using the large-scale UK Biobank dataset. Background: Parkinson's disease (PD) is a neurodegenerative…Electroencephalographic and Functional Magnetic Resonance Imaging Analysis of Daytime Sleepiness in Parkinson’s Disease
Objective: To explore the electroencephalographic (EEG) characteristics and brain functional connectivity patterns in Parkinson's disease (PD) patients with daytime sleepiness. Background: Daytime sleepiness is a…Gauging The Applicability Of The Global Assessment Scale for Wilson’s Disease in Brazil
Objective: To evaluate the clinical applicability of the Global Assessment Scale for Wilson's Disease (GAS-WD) in the Brazilian context. Background: Wilson's disease (WD) is a…Plasma and CSF Autoimmune Markers in Orthostatic Tremor Insights from a Prospective Tertiary Centre Cohort
Objective: To investigate markers of autoimmunity in plasma and cerebrospinal fluid (CSF) in a prospective cohort of patients with OT evaluated at a tertiary movement…Nine-Year Outcome of MRI Guided Focused Ultrasound Thalamotomy in Essential Tremor Patients
Objective: To assess the 9-year outcome of unilateral MRI guided focused ultrasound (MRgFUS) ventral intermediate nucleus thalamotomy in Essential Tremor (ET) patients, with medication resistant…
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