Cerebellar cholinergic denervation relates to impaired gait and cerebellocortical resting-state functional connectivity in Parkinson disease
Objective: The purpose of this cross-sectional study was to investigate the cholinergic denervation of the cerebellum and its contribution to impaired gait and cerebellocortical resting-state…LFP-Based Deep Brain Stimulation Programming and Transition to Adaptive Deep Brain Stimulation in a Patient with Parkinson’s Disease: A Case Report from Thailand
Objective: This case report represents one of the first practical implementations of LFP-guided programming and adaptive DBS in Thailand. Background: Deep brain stimulation (DBS) of…Effects of Targeted Memory Reactivation during Sleep on Motor Memory Consolidation in Parkinson’s Disease
Objective: To study whether targeted memory reactivation (TMR) during sleep improves consolidation of a motor sequence learning task in people with Parkinson’s disease (PD) and…Basal Ganglia Pathway Recruitment Determines Bidirectional Bradykinesia Modulation by DBS in Humans
Objective: Understanding the role of distinct basal ganglia pathways in DBS-elicited modulation of bradykinesia across its indications. Background: Opposing bidirectional effects of selective pathway stimulation…Tongue Shape Complexity in Cantonese Parkinsonian Speech
Objective: To investigate tongue shape complexity across three consonants (/t/, /k/, /s/) in Cantonese people with Parkinson’s disease (PD) using ultrasound tongue imaging (UTI). Background: Articulatory…Sleep Disturbances in Huntington’s Disease A Cross-Sectional Study
Objective: To determine the prevalence of poor sleep quality in HD mutation carriers and to characterize objective sleep parameters. Background: HD is a progressive neurodegenerative…Comparison of Motor Severity in Individuals with Drug-Induced Parkinsonism and Idiopathic Parkinson’s Disease A Systematic Review and Meta-Analysis
Objective: To compare motor severity between individuals with drug-induced Parkinsonism (DIP) and idiopathic Parkinson’s disease (iPD) Background: DIP and iPD may present with similar motor…Speech And Gait In Newly Diagnosed Parkinson’s Disease: Support For Early Rehabilitation
Objective: To describe the prevalence of self-reported speech difficulties in newly diagnosed Parkinson’s disease (PD) and to explore its associations with dysphagia, hypersalivation (HS) and…Regulatory architecture of the SNCA locus in Parkinson’s Disease: Characterization of reported functional mQTL variants in GP2
Objective: To characterize previously reported regulatory variants at the SNCA locus associated with DNA methylation by integrating methylation quantitative trait locus (mQTL) annotations with genotype-derived…Knee Extensor Strength Is Associated with Torque Generation and Mobility in Parkinsonian Disorders
Objective: To examine associations among knee extensor strength (KES), torque generation during knee extension quantified by the area under the torque–time curve (AUC), and functional…
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