2025 International Congress

October 5-9, 2025. Honolulu, Hawaii.

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L-DOPA Induced Iron Accumulation in the Ventral Midbrain: The Roles of Sex and Iron Repletion

R. Serpa, K. Palsa, E. Tufano, T. Helmuth, S. Mills-Huffnagle, M. Kant, J. Connor (Hershey, USA)
L1CAM and TMEM119 enriched Exosomal markers in Parkinson’s Disease and Progressive Supranuclear Palsy: A Prospective Study

A. Roy, S. Brahmachari, A. Pantelyat, L. Rosenthal, V. Dawson, T. Dawson (Gaithersburg, USA)
Language influence on acoustic measures of sustained vowel in patients with Parkinson’s disease and healthy volunteers

I. Khasanov, D. Khasanova (Kazan, Russian Federation)
Large-scale genetic characterization of Parkinson’s disease in the African and African admixed populations

F. Akcimen (Bethesda, USA)
Laryngeal Dystonia, Dopa-Responsive Parkinsonism and Primary Progressive Aphasia with Alzheimer Disease Pathology

A. Eid, R. Perrin, J. Perlmutter, S. Norris (Saint Louis, USA)
LED Light as an Inductor of Optogenetic Activation of Astrocytes in Multiple System Atrophy

F. Kiryukhin, D. Labunskiy, S. Kiryukhina, O. Zheleznikova (Moscow, Russian Federation)
Leveraging a Smartphone-based Platform for Parkinson’s disease Real-world Research: A Multicenter, Cross-sectional Feasibility Assessment Study

Z. Xu, Y. Tang, J. Wang (Shanghai, China)
Leveraging Duty-cycle Based Programming for Deep Brain Stimulation

P. Zeilman, R. Burke, P. Graese, J. Wong (Gainesville, USA)
Levodopa and DBS Produce Discordant Effects on Parkinsonian Features

T. Lee, D. Ramesh, J. Perlmutter, J. Younce (Chapel Hill, USA)
Levodopa Effects In Swedd: Clinical And Kinematic Insights From A Case Report

D. Birreci, L. Angelini, A. Martini, S. Grandolfo, M. de Riggi, S. Aloisio, M. Bologna (Rome, Italy)
Levodopa mediated normalization of cerebello-thalamo-cortical GABA and Glutamate in Parkinson’s disease

S. Prasad, D. Deelchand, M. Kumar, R. Yadav, P. Pal, J. Saini (Bengaluru, India)
Levodopa response in pathology-confirmed Parkinson’s Disease, Multiple System Atrophy and Progressive Supranuclear Palsy

V. Arca, J. Jurkeviciene, S. Wrigley, P. Cullinane, J. Parmera, Z. Jaunmuktane, T. Warner, E. de Pablo-Fernandez (London, United Kingdom)
Lewy Pathology correlates with neuroinflammation in the hippocampus of Synucleinopathy patients in a subregion specific manner

E. Luna, K. Cousins, S. Emrani, K. Luk, V. Lee, E. Lee, D. Weintraub, S. Xie, A. Chen-Plotkin, F. Bennett, D. Irwin (Philadelphia, USA)
Lewy Pathology in the Peripheral Nervous System of SNCA Duplication

G. Beck, M. Yamadera, A. Tarutani, Y. Yonenobu, M. Hasegawa, S. Murayama, H. Mochizuki (Suita, Japan)
Life Course Sleep Duration Trajectories and Risk and Age at Onset of Parkinson’s Disease

Y. Fang, R. Hardy, K. Yaffe, S. Little, C. Tanner, Y. Leng (San Francisco, USA)
Light-Based Therapy in Parkinson’s Disease: The Emerging Role of Optogenetics

M. Helal, M. Gad, R. Eddin Haboush, A. Osman, M. Al-Jumaili, F. Wasia, G. Jamil, M. Elsayed (Zagazig, Egypt)
Lighting the Torch: Dating the Most Common Recent Ancestor of the PINK1 p.L347P Variant Linked to Parkinson’s Disease in Pacific Populations

C. Buchanan, A H. Tan, A. Ahmad-Annuar, S-Y. Lim, YW. Tay, T. Siddique, J. Donnelly, G. Monahan, M. Bruno, R. Minster, S. Viali, F. Fa'Alau, C. Puli'Uvea, N. Edwards, G. Vailahi, R. Roxburgh (Auckland, New Zealand)
Likelihood to consent within the PREDICT-PD cohort: Identifying potential barriers or promoters of involvement in longitudinal Parkinson’s research

S. Meyer, R. Benabderrazik, H. Chohan, A. Shahid, R. Lathey, L. Smith, C. Simonet, L. Pérez-Carbonell, E. de Pablo-Fernandez, A. Schrag, A. Noyce (London, United Kingdom)
Limb Myorhythmia in a Patient With Anti-LGI-1 Encephalitis

V. Mazo, P. Atit, S. Aradi, A. Rivera Cruz (Tampa, USA)
Lingual tremor secondary to ischemic stroke of the left middle cerebral artery: Another movement disorder with cortical localization?

S. Garcia, A. Tena, J. Sanchez (MADRID, Spain)
Linking Adolescent Brain Development To Parkinson’s Disease Risk Using Machine Learning On Polygenic Risk Scores

L. Liu, R. Zhu, E. Yu, X. Liu, R. Ge, A. Dagher, Z. Gan-Or (Montreal, Canada)
Lived Experiences in early clinical PD: Developing a Framework of a Novel Patient-reported Outcome (PRO) Fit-for-purpose for Disease Modification Therapeutic Trials

T. Mestre, J. Ding, N. Lapelle, G. Stebbins (Chicago, USA)
Living Deep Brain Stimulation for External Control of Striatal Dopamine

K. Yankson, D. Chouhan, J. Duda, K. Cullen (Philadelphia, USA)
Local field potential vs image guided programming: clinical trial for optimization the deep brain stimulation in Parkinson’s disease

A. Martínez Reyes, J. Bejarano Hernández, A. Cadena Fernández, C. Lázaro Hernández, F. Valldeoriola Serra, A. Sánchez Gómez (Barcelona, Spain)
Loneliness accelerates parkinsonism decline in parkinsonian community-dwelling older adults

D. Gonzalez, M. Wilson, M. Tosin, M. Roy, C. Goetz (Chicago, USA)
Long term real-world monitoring supports the superiority of adaptive deep brain stimulation: preliminary data on three patients with Parkinson’s disease

L. Caffi, R. Habib, L. Borellini, E. Mailland, F. Cogiamanian, M. Arlotti, L. Rossi, S. Bonvegna, C. Palmisano, S. Marceglia, A. Priori, G. Pezzoli, M. Locatelli, IU. Isaias (Würzburg, Germany)
Long-term analysis of subthalamic local field potentials (LFP) in Parkinson’s disease: Insights into circadian rhythms, medication, and personalized treatment effects

V. Livneh, R. Naivelt, M. Zutta, Z. Katzir, R. Monteoriano, I. Strauss, K. Avirame, A. Socher, G. Morris, I. Maidan (Tel Aviv, Israel)
Long-Term Benefits of Weekly Group Physiotherapy in Slowing Parkinson’s Progression:A 12-Month Non-Randomized Controlled Trial

E. Tardelli, M. Piemonte, B. Rosa, P. Igarashi, C. Dias (São Paulo, Brazil)
Long-Term Dementia Risk in the General Parkinson Disease Population

J. Maple-Grødem, ø. Rustan, D. Bäckström, M. Camacho, C. Counsell, I. Dalen, L. Forsgren, R. Lawson, A. Macleod, C. Williams-Gray, A. Yarnall, OB. Tysnes, G. Alves (Stavanger, Norway)
Long-Term Effect of Dopaminergic Treatment on gait in De Novo Parkinson’s Disease: the DNA mobile health technology longitudinal study

A. Pilotto, C. Zatti, A. Rizzardi, C. Hansen, J. Gerritz, R. Romijnders, M. Catania, A. Lupini, W. Maetzler, A. Padovani (Brescia, Italy)
Long-Term Effect of Opicapone in Parkinson’s Patients Without Motor Complications: 1.5-year EPSILON Study Findings

J. Ferreira, O. Rascol, F. Stocchi, A. Antonini, H. Brigas, J. Moreira, JF. Rocha, M. Fonseca, J. Holenz, W. Poewe (Lisbon, Portugal)
Long-Term Effectiveness and Tolerability of Vatiquinone in an Adult Friedreich’s Ataxia Population

C. Werner, S. Perlman, J. Blaize, M. Rance, J. Cherry, O. Zhang, L. Golden, D. Lynch, T. Zesiewicz (Frankfurt, Germany)
Long-term effects of a periodic intensive rehabilitation program in People with Parkinson’s Disease

Y. Yamaguchi, J. Ogawa, K. Kakegawa, M. Matsuda (Ginza, Chuo-ku, Japan)
Long-Term Effects of Telerehabilitation on Functional Mobility and Quality of Life in Parkinson’s Disease: A Systematic Review

A. Elsayed, D. W. Ismail, H. Elshazly, Y. M.HUSSEINY, S. Elrobeigi, Y. Hamdi, M. M. Elsayed (Mansoura, Egypt)
Long-term outcomes of subthalamic Deep Brain Stimulation in LRRK2 patients

C. Lazaro Hernandez, A. Garrido Pla, A. Sanchez Gomez, A. Cadena Fernandez, J. Bejarano Hernandez, F. Valldeoriola Serra (Barcelona, Spain)
Long-term results of pallidal deep brain stimulation in patients with Huntington’s disease

A. Gamaleya, A. Poddubskaya, S. Asriyants, A. Tomskiy (Moscow, Russian Federation)
Long-Term Safety and Efficacy of Valbenazine for Treating Huntington’s Disease Chorea

E. Furr Stimming, E. Kayson, S. Karpuram, J. Goldstein, S. Hinton, O. Klepitskaya, H. Zhang, E. Dunayevich, D. Haubenberger (Houston, USA)
Long-Term Therapeutic Effect of Botulinum Neurotoxin Type A (BoNT-A) in Cervical Dystonia: A Case Series.

R. Lopez-Castellanos, R. Lopez-Contreras (Boston, USA)
Longitudinal Analysis of BRAIN test in isolated REM sleep behaviour disorder with and without hyposmia.

H. Chohan, T. Tocino, L. Pérez-Carbonell, G. Leschziner, J. Bestwick, A. Schrag, A. Noyce, C. Simonet (London, United Kingdom)
Longitudinal Analysis of Cognitive Changes in Parkinson’s Disease Subjects at Risk of Developing Probable REM Sleep Behavior Disorder (RBD)

A. Basu, J. Ruiz Tejeda, R. Rajmohan, N. Phielipp (Irvine, USA)
Longitudinal Analysis of Disease Progression in GBA-Associated Early-Onset Parkinson’s Disease

YM. Sun, PH. Li, ZY. Qi, FT. Liu, JJ. Wu, J. Wang (Shanghai, China)
Longitudinal Brain Morphometric Trajectories Across Parkinson Disease Clinical Subtypes

A. Eid, S. Grossen, A. Tanenbaum, J. Hood, H. Hwang, T. Cash, C. Lessov-Schlaggar, J. Jackson, P. Kotzbauer, J. Perlmutter, M. Campbell (Saint Louis, USA)
Longitudinal Effects of Initial Deep Brain Stimulation Settings on Force-Tracking Brain Activation and Motor Performance in Parkinson’s Disease

A. Vijayakumari, C. Piccinin, T. Lopez Gonzalez, J. Alberts, P. Bhattacharyya, M. Lowe, B. Walter (Cleveland, USA)
Longitudinal FDG-PET Study of Metabolic Trajectories and Connectivity Alterations in Multiple System Atrophy

Y. Zhao, H. Lin, X. Li, F. Liu, J. Wang (Shanghai, China)
Longitudinal MRI Study of Hippocampal Subfields Morphometry in Early Parkinson’s Disease

T. Wu, S. Ng, T. Teo, X. Choi, D. Heng, S. Neo, Z. Xu, K. Tay, W. Au, E. Tan, L. Chan, L. Tan, T. Welton (Singapore, Singapore)
Longitudinal Remote Monitoring with Wearable Technology in Parkinson Disease: Initiation of A Dyskinesia Insight Network Observational Study

R. Gilron, A. Hare, M. Grall, P. Qin, S. Isaacson (San Francsico, USA)
Low Frequency Directional Deep Brain Stimulation of the Cuneiform Nucleus for Levodopa-Resistant Freezing of Gait: Six-Month Outcomes.

C. Luca, V. Torres Ballesteros, M. Baumgartner, J. Gujral, L. Qiu, B. Noga, J. Jagid, I. Cajigas (Miami, USA)
Low Level of Serum Total Cholesterol Predicts Mortality in Early-stage Multiple System Atrophy: a Prospective-cohort Study

JX. Huang, LY. Zhang, QR. Jiang, SC. Wang, Y. Xiao, NN. Che, JY. Lin, B. Zhao, YF. Cheng, CY. Li, HF. Shang (Chengdu, Sichuan, China)
Low Nutritional and Metabolic Abnormalities Predict the Incidence of Parkinson Diseases: A Large Prospective Cohort Study

J. Fu, X. Chen, H. Shang (Chengdu, China)
Low-frequency pallidum evoked potential dynamics as a prospective biomarker for Parkinson’s disease

B. Mohanty, N. Perera, K. O'Neill Iii, S. Alberico, M. Hill, D. Bauer, B. Pobiel, J. Froula, D. Darrow, M. Park, J. Wang, L. Johnson, J. Aman, J. Vitek (Minneapolis, USA)
Lower Eyelids Botulinum Injections: Improving Dry Eye and Prolonging Therapeutic Effect

M. Cohen, L. Berkovitz, H. Totah, Y. Shechter, G. Yahalom (jerusalem, Israel)
LRRK2 antisense oligonucleotide (BIIB094/ION859) impact on cerebrospinal fluid biomarkers in Parkinson’s disease patients

O. Mabrouk (cambridge, USA)
LRRK2 I1371V Mutation Induces ER Stress, Mitochondrial Dysfunction, and Impaired Mitophagy in Parkinson’s Disease Astrocytes

R. Banerjee, V. Holla, N. Kamble, R. Yadav, P. Pal, I. Datta (Bangalore, India)
LRRK2 Mutation in a Patient with NMDA and GAD 65 Antibodies

S. Ticehurst Corona, F. García Hernández (Mexico City, Mexico)
LRRK2 Pathway Inhibition By NEU-411, a Potent, Selective, CNS-Penetrant LRRK2 Inhibitor In Healthy Participants

C. Wong, S. Dheerendra, T. Dang, F. Nahab, J. Zheng, S. Savage, Z. Pei, C. Wynne, S. Jackson, L. Desnoyers (South San Francisco, USA)
LRRK2 Polymorphisms and Associations with Parkinson’s Disease in Participants of East Asian, Southeast Asian, and European Descent

S. Nguyen, R. Edillor, J. Ruiz-Tejeda, R. Rajmohan, N. Phielipp (Irvine, USA)
Lung Function and the Risk of Parkinson’s Disease: A Population-based Cohort Study

JY. Liu, SC. Wang, XT. Zheng, SR. Zhang, QR. Jiang, CY. Li, HF. Shang (Chengdu, Sichuan, China)
Lysosomal Lipid Dysregulation in Parkinson’s Disease: Genetic and Medication Effects in CSF Metabolomics

J. Suh, R. Maciuca, E. Macklin, S. Davis, J. Kluss, N. Xia, H. Yazd, M. Schwarzschild, S. Huntwork-Rodriguez (South San Francisco, USA)

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