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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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2025 International Congress » Parkinson's Disease: Disease mechanisms

Meeting: 2025 International Congress

A retrospective study on thyroid dysfunction mimicking Parkinsonian symptoms

D. Mukhammedaminova, L. Kenjaeva (Tashkent, Uzbekistan)

Advancements in Microbiome Research: Total Microbial Load, Differential Absolute Abundance, and Correlations with Immune Transcriptomics

B. Palushaj, M. Chakraborty, I. Porter, G. Reynolds, E. Brooks, Z. He, A. Bhatt, K. Poston (Palo Alto, USA)

Alpha-Synuclein Aggregates in the Olfactory Epithelium of Subjects with Parkinson Disease, Dementia, COVID-19, and in Aged Controls

J. Tomlinson, N. Lengacher, A-K. Jochum, J. Franz, L. Flatz, B. Mollenhauer, C. Stadelmann, J. Woulfe, M. Schlossmacher (Ottawa, Canada)

Assessment of the impact of the diabetic features hyperglycemia and insulin resistance on fibril induced synucleinopathy

S. Nelson, G. Barajas, A. Cole-Strauss, M. Kubik, C. Kemp, C. Sortwell, J. Patterson (Grand Rapids, USA)

Association Between Heterozygous Loss-of-Function Variants in the MCOLN1 Gene and α-Synucleinopathies

CX. Ying, XH. Chen, ZD. Cen, W. Luo (Hangzhou, China)

Cerebrospinal fluid measured α-synuclein is related to metabolite profile in the serum and CSF

K. Paul, D. Jones, B. Ritz (Los Angeles, USA)

Characterizing the Neural Signature of Parkinsonian Freezing of Gait During an Immersive Virtual Reality Paradigm

M. Miller Koop, A. Rosenfeldt, K. Scelina, L. Scelina, C. Waltz, A. Bazyk, V. Berki, K. Baker, N. Malan, S. Nagel, B. Walter, J. Liao, K. Baker, J. Alberts (Cleveland, USA)

Clinical Progression and Genetic Pathways in Body-First and Brain-First Par-kinson’s Disease

M. Passaretti, D. Veréb, M. Mijalkov, Y. Chang, H. Zhao, J. Sun, B. Zufiria Gerbolés, G. Volpe, N. Rivera, M. Bologna, J B. Pereira (Stockholm, Sweden)

Cognitive Load Modulates Excitability of Subthalamic Motor Circuitry in Parkinson’s Disease

V. Zapata, G. Marin, D. Parra, J. Ailsworth, J. Cordoba, E. Chen, M. Lowe, S. Jones, B. Walter, R. Rammo, S. Nagel, A. Machado, K. Baker, D. Escobar (Cleveland, USA)

Computer Vision Quantification of Repeated Finger Tapping Demonstrates Aberrant Plasticity in Parkinson’s Disease

D. Newbold, U. Kang (New York, USA)

Coping with Parkinson’s Disease through the Lens of Personality Systems Interactions (PSI) Theory: Two Case Studies

E. Wünnenberg, N. Baumann (Trier, Germany)

Correlations of catecholamine metabolites and alpha-synuclein by nigral stimulation in Parkinson’s disease model rat

T. Yamamoto, R. Sakakibara, T. Uchiyama, S. Kuwabara (Chiba, Japan)

CSM-101 is a Small Molecule Agonist of TRPML1 for Parkinson’s-Related Disorders

L. Murphy, J. Fortanet, D. Baird, T. Lehmberg, K. Skerry, M. Broadus (Boston, USA)

Differential Motor Cortex Compensation in Parkinson’s Disease based on Putamen Neurodegeneration Laterality: Insights from EEG and [¹⁸F]FDOPA PET/CT

K. Lorek, J. Mączewska, L. Królicki, K. Markowska, M. Koszewicz, S. Budrewicz, M. Chalimoniuk, J. Marusiak (Wroclaw, Poland)

Differentiated approach to treatment and diagnosis of Parkinson’s disease

MRA. Abduvahabovna, ZUJ. Jahongir Qizi (Fergana, Uzbekistan)

Differentiated approach to treatment and diagnosis of Parkinson’s disease.

ZUJ. Jahongir Qizi, RMA. Abduvahabovna (Fergana, Uzbekistan)

Does the cerebellum compensate to enable motor learning in Parkinson’s Disease?

PC. Iyer, BE. Fisher (Los Angeles, USA)

Dual-task gait digital assessment unmask the association between dopaminergic deficits and gait parameters in early and prodromal Parkinson’s Disease

A. Pilotto, C. Zatti, A. Rizzardi, A. Galli, C. Hansen, J. Geritz, R. Rominjnders, E. Schaeffer, M. Catania, A. Lupini, T. Comunale, E. Premi, M. Pasolini, S. Lucchini, F. Brertagna, B. Paghera, S. Caminiti, D. Perani, D. Berg, W. Maetzler, A. Padovani (Brescia, Italy)

Ferritin-related Brain Iron Deposition in Parkinson’s Disease Involves α-Synuclein Pathology

L. Luo, D. Su, Z. Yu, T. Feng (Beijing, China)

Gait Imagination and Gait Observation Related Midfrontal Oscillations in People With Parkinson’s Disease and Freezing of Gait

A. Singh, M. Leedom (Vermillion, USA)

GBA Mutations Alter Subthalamic and Nigral Neural Activity in Parkinson’s Disease

N. Pozzi, I. Hanafi, F. Kremer, T. Musacchio, M. Reich, C. Palmisano, I. Isaias, J. Volkmann, M. Muthuraman, P. Capetian (Würzburg, Germany)

Investigating the cellular consequences of the G2385R LRRK2 variant

P. Lewis, S. Herbst (London, United Kingdom)

Investigation of the mode of action of a new device for the application of therapeutic vibro-tactile stimulation to the fingertips on brain activity

K. Frey, J. Hügel, L. Lowinski, G. Rennert, C. Castañeda González, I. Klingmann, C. Böhler, C. Hauptmann (Plankstadt, Germany)

NIH funds Gut-Brain Parkinson’s Disease Consortium

C. Goetz, L. Becker, A. Bharucha, E. Chang, A. Keshavarzian, B. Kuo, K. Newby, K. Poston, L. Sanders, R. Savica, A. Sharma, A. Videnovic, L. Wruck, T. Xie (Chicago, USA)

Patient-derived α-synuclein seed amplification as a tool for evaluating small molecule aggregation inhibitors for Parkinson’s disease and Lewy Body Dementia therapeutics

K. Luk, B. Li, S. Song, N. Newman (Cambridge, USA)

Quercetin Reduces mtDNA Release in PRKN-Deficient and Oxidatively Stressed SH-SY5Y Cells

G. Agyeah, J. Ghelfi, L. Gallucci, K. Wasner, P. Antony, A. Rakovic, S. Pereira, A. Grünewald (Belval Esch-sur-Alzette, Luxembourg)

Targeting IGF2 Signaling for Immune Modulation of Microglia in Parkinson’s Disease

T. Huerta, V. Urbina, C. Aguilera, P. Chana, R. Vidal (Santiago, Chile)

The A53T mutation in alpha-synuclein impairs astrocytic metabolism and inflammatory response

S L. Pereira, M. Tziortziou, P. Mulica, S. Delcambre, L. Gallucci, L. Neises, M. Soudy, E. Glaab, M. Mendes, G. Dittmar, J. Meiser, A. Grünewald (Esch-sur Alzette, Luxembourg)

The effect of trial numbers on prism adaptation in Parkinson’s disease

K. Taneda, T. Shimizu, N. Tokuda, S. Moriyasu, T. Nakamura, T. Murakami, Y. Ugawa, R. Hanajima (Yonago, Japan)

The Feedback Loop: Illness Perceptions and Motor Complications in Parkinson’s

V. Azoidou, L. Smith, A. Noyce, C. Simonet (London, United Kingdom)

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