Neuroprotective Epigenetic and DNA-Repair Molecular Mechanisms of Acetyl-L-Carnitine and Astaxanthin Against 6-OHDA Induced Parkinsonism in Aged Rats
Objective: Present study was designed to delineate the neuroprotective epigenetic and DNA-damage-repair molecular mechanisms of acetyl-L-carnitine (ALC) and astaxanthin (ASX) against 6-OHDA-induced neurotoxicity in aged…The feasibility of detailed phenotyping of muscle mitochondrial respiratory chain function and content in Parkinson’s disease
Objective: We aimed to determine: 1) the feasibility of obtaining and characterising skeletal muscle; and 2) if muscle mitochondrial respiratory chain (MRC) function and content…Disease progression characterized by motor performance, dopaminergic neurodegeneration and T cell infiltration in the transgenic hm2-α-SYN-39 mouse model of Parkinson´s disease
Objective: To study disease progression in the transgenic (tg) hm2-α-SYN-39 mouse model of Parkinson´s disease (PD) by assessment of motor performance, dopaminergic neurodegeneration and T…Relationship between tumor and very slow Parkinson`s disease progression
Objective: We evaluate the Parkinson`s disease patients with very slow progression. One of their clinical features are the medical history of tumor. Background: Some cancer…Age at onset and Parkinson’s disease progression
Objective: Explore whether age at onset of Parkinson’s disease influences the rate of early disease progression. Background: In cross-sectional studies, older age at onset has…Effects of a community-based adapted boxing program on physical capacity and quality of life in individuals with Parkinson disease over a 12 month period
Objective: The main objective was to assess long-term effects of a community-based adapted boxing program on physical capacity and QoL in individuals with mild, or…Predictors of transfer to facility or nursing home after discharge of inpatients with Parkinson’s disease: A Japanese single center retrospective study
Objective: To investigate the reasons for hospital admissions for Parkinson's disease (PD) patients and to determine the predictors of transfer to facility or nursing home…Vascular age calculated by pulse wave velocity may help predict the prognosis after Deep brain stimulation surgery in patients with Parkinson’s disease
Objective: We aimed to examine the relationship between pulse wave velocity (PWV) at pre- deep brain stimulation (DBS) stage and symptoms change at post-DBS stage.…Application of a Simple Parkinson’s Disease Risk Score in a Longitudinal Population Based Cohort
Objective: To apply the PREDICT-PD algorithm of risk indicators for Parkinson’s disease (PD), in a prospective community-based study (the Bruneck Study), representative of the general…The impact of motor and non-motor symptoms on walking capacity in people with Parkinson’ disease
Objective: This study aimed to evaluate the motor and non-motor factors associated with walking capacity in people with Parkinson’s disease (PwPD). Background: Walking over short…
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