Profiling of lipoproteins and associated lipids in serum samples from Idiopathic REM Sleep Behavior Disorder patients to identify biomarkers for Parkinson’s disease
Objective: To perform a lipidomic profile in serum samples from IRBD patients collected before and after their conversion to PD and DLB, in order to…Exosomes from patients with Parkinson’s disease are pathological in mice
Objective: To verify the hypothesis that serum-derived exosomes from patients with Parkinson’s disease (PD) may serve as risk carriers for inter-neuronal risk transmission, eventually resulting…Alpha-synuclein expression and cytokine profile in blood of patients with Lewy body dementias
Objective: To examine alpha-synuclein expression in CD45+ and cytokine levels in blood of patients with dementia with Lewy bodies (DLB), Parkinson's disease dementia (PDD). Background:…Microglia as modulators of exosomal alpha-synuclein transmission
Objective: It is highly desirable to make clear the underlying mechanism of exosomes-involved communication in the synucleinopathy pathogenesis. Background: Emerging evidence suggests that exogenous pathogenic…Behavioural aspect of transgenic Drosophila melanogaster as a model of Parkinson’s disease treated by Ropinirole alginate nanocomposite
Objective: To evaluate the behavioural changes in transgenic Drosophila melanogaster as a model of Parkinson’s disease treated by different doses of Ropinirole alginate nanocomposite (RANC).…Decreased serum alpha-synuclein in patients with Restless Legs Syndrome and association with SNCA-Rep1 polymorphism
Objective: To investigate whether α -synuclein levels are altered in serum and saliva in patients with RLS and explore influence of the SNCA-Rep1 microsatellite repeat…Impaired lysosomal catabolism of alpha-synuclein in parkinsonian LRRK2(R1441G) mutant mouse embryonic fibroblasts
Objective: Using a unique fluorescence-based flow cytometry assay on LRRK2(R1441G) mutant mouse embryonic fibroblasts (MEFs) to elucidate whether pathogenic LRRK2 mutation affects cellular lysosomal degradation…Alpha-synuclein seeding activity in blood samples from synucleinopathy patients
Objective: Utilize a cell-based assay to determine whether a-syn seeding activity can be amplified and detected from blood components from patients with Parkinson’s disease (PD)…Appendectomy and risk of Parkinson’s disease: A meta-analysis using real-world evidence
Objective: This meta-analysis is aimed to explore the association between appendectomy and Parkinson’s disease (PD) risk. Background: Parkinson’s disease is recently recognized as a systematic…Autonomic features in E46K-SNCA carriers
Objective: To evaluate structural and functional integrity of small autonomic nerve fibers and phosphorylated alpha-synuclein (p-syn) deposition in the skin of E46K-SNCA carriers as compared…
- « Previous Page
- 1
- …
- 39
- 40
- 41
- 42
- 43
- …
- 60
- Next Page »