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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Amantadine"

  • 2019 International Congress

    Utilization patterns of Amantadine in Parkinson’s Disease patients enrolled in the French COPARK study

    S. Perez-Lloret, L. Negre-Pages, P. Damier, A. Delval, P. Derkinderen, A. Destée, W. Meissner, F. Tison, O. Rascol (Bordeaux, France)

    Objective: To explore amantadine IR utilization patterns in the French COPARK study. Background: Immediate release (IR) amantadine is marketed for the treatment of early and…
  • 2019 International Congress

    Safety of Gocovri in Clinical Practice: One-year Post-launch Pharmacovigilance Data

    C. Tanner, R. Pahwa, V. Vandevoorde, K. Wehrman, R. Elfont (San Francisco, CA, USA)

    Objective: To assess the real-world safety profile of Gocovri® (amantadine) extended release capsules one year post-launch. Background: Gocovri received FDA approval in August 2017 for…
  • 2019 International Congress

    High dose amantadine therapy may cause increased falling in Parkinson’s patients

    L. Verhagen Metman (Chicago, IL, USA)

    Objective: To report a possible association between high dose amantadine and increased falling in patients with Parkinson’s disease (PD). Background: Amantadine is used in PD…
  • 2018 International Congress

    Final Safety Results of EASE LID 2 Study: Long Term Open-Label Study of ADS-5102 for Dyskinesia in Parkinson’s disease (PD) patients

    S. Isaacson, R. Pahwa, C. Tanner, R. Hauser, W. Oertel, R. Johnson, L. Felt, M.J. Stempien, R. Patni (Boca Raton, FL, USA)

    Objective: The primary objective of this study was the safety and tolerability of ADS-5102 in PD patients with dyskinesia. Secondary efficacy outcome measures included MDS-UPDRS,…
  • 2018 International Congress

    Impact of Dyskinesia in Parkinson’s Disease (PD) on Activities of Daily Living (ADLs) and Daily Tasks: Results from Pooled Phase 3 ADS-5102 Clinical Trials

    R. Pahwa, S. Isaacson, J. Jimenez-Shahed, I. Malaty, A. Deik, R. Gandhy, R. Johnson, R. Patni (Kansas City, KS, USA)

    Objective: To assess the impact of dyskinesias in PD on ADLs and the effects of ADS-5102 (amantadine) extended release capsules on these impairments. Background: ADS-5102…
  • 2018 International Congress

    Final MDS-UPDRS, Part IV Results of the EASE LID 2 Study: Long Term, Open-Label Study of ADS-5102 for Dyskinesia in Parkinson’s disease (PD) patients

    R. Hauser, R. Pahwa, C. Tanner, W. Oertel, R. Johnson, L. Felt, MJ. Stempien, R. Patni (Tampa, FL, USA)

    Objective: An objective of this study was to evaluate the long-term duration of ADS-5102 effect on dyskinesia as assessed by the Unified Parkinson’s Disease Rating…
  • 2018 International Congress

    Assessing the potential cost-effectiveness of ads-5102 (Amantadine HCl) for the treatment of dyskinesia in Parkinson’s disease patients

    R. Pahwa, L. Garrison, M. Zimmerman, R. Johnson, J. Nguyen, M. Li, R. Patni (Kansas City, KS, USA)

    Objective: This economic evaluation projects the likely cost-effectiveness of ADS-5102 in comparison to the current standard of best supportive care. Background: In August, 2017, the…
  • 2018 International Congress

    Amantadine extended release (Gocovri) reduces dyskinesia and bradykinesia: Evaluation of clinical response with the wearable PKG (Personal Kinetigraph) watch

    N. Chhabria, S. Isaacson, K. Lyons, R. Pahwa (Boca Raton, FL, USA)

    Objective: To determine the effect of bedtime high-dose amantadine extended release (Gocovri) in 50 consecutive patients experiencing motor fluctuations and dyskinesia. Background: Amantadine extended release…
  • 2018 International Congress

    Dopaminergics are alternative for the treatment of Bell`s paralysis in acute period

    A. Azimov, R. Sadykov, G. Rakhimbaeva, F. Azimov (Tashkent, Uzbekistan)

    Objective: To study the possibility of using dopaminergic medicines for the treatment of Bell`s paralysis in acute period. Background: In previous reports we conjectured that…
  • 2017 International Congress

    Interim Results of an Ongoing Open-label Safety Study of ADS-5102 (amantadine hydrochloride) Extended-Release Capsules for Treatment of Levodopa-Induced Dyskinesia (LID) (EASE LID 2 Study)

    R. Hauser, R. Pahwa, C. Tanner, W. Oertel, S. Isaacson, M.J. Stempien, L. Felt, R. Johnson (Tampa, FL, USA)

    Objective: Characterize the long-term safety and tolerability of 340 mg of ADS-5102 administered once daily at bedtime, for the treatment of LID in Parkinson’s disease…
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