Apathy produces selective deficits in cognitive function when controlling for depression in patients with Parkinson’s disease
Objective: To compare differences in the mean cognitive impairment (CI) of patients with and without clinically significant apathy in PD, PD-mild cognitive impairment (PD-MCI), and…Clinical correlates of apathy in Parkinson´s disease
Objective: To investigate the demographic and clinical correlates of apathy in a group of patients from a Movement Disorders clinic in Latin America. Background: Apathy…Neurophysiological Underpinnings of Apathy in Parkinson’s Disease Versus Depressive Disorders: A Comparative Study
Objective: The manifestation of apathy in neurological and psychiatric conditions such as Parkinson's Disease (PD) and depressive disorders presents a significant clinical challenge. This study…Apathy in de novo Parkinson’s disease improves after the first years with dopaminergic treatment.
Objective: to define the evolution of apathy and other neuropsychiatric symptoms in patients with early Parkinson’s disease (PD). Background: Apathy is a common neuropsychiatric symptom…Impact of Community Boxing Program on Non-motor Symptoms in Individuals with Parkinson’s Disease
Objective: The purpose of this intervention was to assess the impact of boxing on non-motor symptoms (NMS) in PD. Background: For persons with Parkinson’s Disease…Improving Neuropsychiatric Comorbidity in Geriatric Spinocerebellar Ataxia
Objective: This study evaluates neuropsychiatric comorbidity in spinocerebellar ataxia (SCA) and highlights key aspects of management in the geriatric population. It discusses efficacy of neuropsychotropic…Noradrenaline treatment of apathy and impulsivity in participants with Progressive Supranuclear Palsy syndromes (NORAPS). A Phase II clinical trial – ISRCTN99462035.
Objective: The NORAPS Phase II clinical trial seeks to demonstrate safety, tolerability and efficacy of atomoxetine in Progressive Supranuclear Palsy (PSP). Background: PSP is a…Connectivity Profile for Increased Apathy Following Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease
Objective: To describe the structural connectivity profile associated with apathy following subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson’s disease (PD). Background: While STN-DBS…Feasibility of Reliable, Remote Assessment of a 13-year-old Boy Who Stopped Talking
Objective: To assess the feasibility of reliable, remote assessments of videos of a 13-year-old boy who stopped talking Background: The sudden absence of speech in…Identifying neural biomarkers of motivated behavior in Parkinson’s disease using sensing-capable DBS devices
Objective: To investigate neural correlates of motivated, goal directed behavior within the basal ganglia. Background: Apathy is a common and debilitating complication of Parkinson’s disease…
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