Are Lewy bodies associated with sympathetic pathology in dementia subjects?
Objective: Determine if Alzheimer disease (AD) subjects with Lewy bodies show sympathetic cardiac denervation. Background: Comorbid Lewy body (LB) pathology is very common in AD,…Cardiac sympathetic denervation can predict the wearing-off phenomenon in patients with Parkinson’s disease
Objective: To investigate whether cardiac sympathetic denervation increases the risk of the early wearing-off phenomenon in Parkinson's disease (PD). Background: Recent studies have suggested that…Heart rate variability and Sympathetic skin response in Parkinson’s disease
Objective: To assess the neurophysiologic cardiac autonomic findings and Sympathetic skin response (SSR) in a Tunisian cohort of Parkinson's disease (PD). Background: Prevalence of dysautonomia…Autonomic Dysfunction in Parkinson’s Disease: Role of New Surrogate Markers
Objective: The physiology of respiration is modulated by autonomic efferent neurons and circulating hormones. A continuous ambulatory monitoring of various respiratory parameters helps in early…Proteomic analysis of tear-fluid reveals disease-specific patterns in patients with Parkinson’s Disease
Objective: In this study, we set out to analyse changes of tear fluid (TF) proteome in Parkinson's Disease (PD) patients compared to age-matched controls (AMC)…Two-year prospective study reveals that gut dysbiosis predicts progression of Parkinson’s disease
Objective: This study is to examine whether intestinal microbiota correlate with pathology progress of PD severity and change of gut microbiota for 2 years. Background:…Nonmotor disorders in Parkinsonism: Experience in Kyrgyz Republic
Objective: Investigate existence and evidence of the nonmotor disorders, particularly neuropsychological disorders and autonomic dysfunctions in PD and vascular Parkinsonism patients. Background: Nonmotor disorders accompany…Normal “heart” in Parkinson’s disease: Is this a distinct clinical phenotype?
Objective: The aim of this study was to investigate whether non-motor manifestations of Parkinson’s disease (PD) differ between patients with normal and abnormal myocardial metaiodobenzylguanidine (MIBG)…Intranasal delivery of insulin for the restoration of memory signaling in Alzheimer disease
Objective: Objective of this study is to develop delivery-system to overcome BBB by employing novel, non-invasive approach via nasal route. The olfactory neural pathway provides…The autonomic nervous system in Friedreich´s Ataxia: preliminary findings
Objective: To investigate the autonomic function in Friedreich´s ataxia (FRDA) Background: FRDA is a hereditary neurodegenerative disorder characterized by progressive gait ataxia, limb dysmetria, dysarthria…