Mutant WDR45 links NBIA to impaired autophagy, mitochondrial dysfunction and oxidative stress
Objective: To examine the impact of mutant WDR45 on autophagy,mitochondrial function,and oxidative stress capacity in patient's fibroblasts. Background: Mutations in the WD repeat domain 45…Iron accumulation in a Wilson disease patient: Longitudinal 7T MRI and transcranial sonography study
Objective: To investigate longitudinal changes in clinical symptoms, 7T MRI and transcranial sonography (TCS) during chelating treatment in a Wilson disease (WD) patient. Background: Pathophysiological…Vascular degeneration in Parkinson’s disease
Objective: To determine the role vascular degeneration in human Parkinson's disease (PD). Background: We have previously reported endothelial degeneration in the PD. Current study examined…Disrupted motor memory in Parkinson’s disease
Objective: We sought to investigate the differences in motor adaptation and motor memory between people with Parkinson's disease (PD) and healthy age-matched controls by using…Clinical aspects of postural instability in Parkinson’s disease
Objective: To identify the clinical features of postural instability by PD patients. Background: Postural instability (PI) to maintain body balance while walking. The causes of…Dopaminergic medication affects choice bias in Parkinson’s disease
Objective: Assess dopaminergic effects on choice bias in Parkinson's disease (PD). Background: Bradykinesia, rigidity and resting tremor are the core symptoms of PD, but many…A whole brain anatomical network model and its application in PD research
Objective: To build a frame of whole brain anatomical network for incorporating different data from different studies with different brain parcellations and resolutions, to evaluate…Impact of chronic LD treatment on metabolism, blood flow and blood-brain barrier permeability in the 6-OHDA rat model
Objective: To determine the effects of chronic LD treatment and induction of dyskinesias on cerebral metabolism, blood flow and blood-brain barrier permeability in 6-OHDA rat…Urate and homocysteine: Changes in motor and cognitive symptoms in newly diagnosed Parkinson’s disease
Objective: 1) To determine serum urate and homocysteine concentration at baseline, 18 and 36 months in control and PD participants. 2) To determine if urate…Impaired temporal coupling of action and perception in Parkinson’s disease
Objective: To study in Parkinson's disease (PD) the dependence of saccadic and perceptual reaction times (SRT and PRT) upon the temporal asynchrony (TA) between central…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.