Neuropsychiatric profile of progressive supranuclear palsy phenotypes
Objective: To analyze neuropsychiatric symptoms among phenotypes of patients with Progressive supranuclear palsy (PSP) in movement disorder centers in Colombia and Mexico. Background: Progressive supranuclear…Noradrenaline treatment of apathy and impulsivity in participants with Progressive Supranuclear Palsy syndromes (NORAPS)
Objective: The NORAPS phase II study (ISRCTN99462035) investigates the safety, tolerability and efficacy of atomoxetine in Progressive Supranuclear Palsy (PSP). Background: PSP is a neurodegenerative…The Feedback Loop: Illness Perceptions and Motor Complications in Parkinson’s
Objective: To explore the relationship between motor complications, illness perceptions and cognitive beliefs about symptoms in people with Parkinson's disease (PwP). Background: Around 50% PwP…Cognitive and Neuropsychiatric Dysfunction is Associated with Corticostriatal Synucleinopathy in the Alpha-Synuclein Preformed Fibril Rat Model of Parkinson’s Disease
Objective: To investigate the role of corticostriatal synucleinopathy on behavioral function in an alpha-synuclein preformed fibril (a-Syn PFF) rat model of Parkinson’s disease (PD). Background:…Exploring Visual Scanning Behavior and Novelty Seeking in Parkinson’s Disease: A Pilot Study
Objective: To assess the feasibility of eye-tracking metrics in a Visual Paired Comparison (VPC) task as biomarkers for impulsivity in Parkinson's disease (PD) and to…VPS13C: a Modifier Gene causing Suboptimal Response to Levodopa in Early-Onset Parkinson’s Disease
Objective: To describe a retrospective clinical study of four cases carrying heterozygous pathogenic variants in the VPS13C gene with a clinical diagnosis of Early-Onset Parkinson’s…Efficacy and Feasibility of Telemedicine-Based Dietary Intervention vs. Outpatient Supervision for Drug-Resistant Multiple System Atrophy in Postmenopausal Women During COVID-19
Objective: This study aimed to evaluate the feasibility, safety, and patient satisfaction of initiating and following up on MAD via telemedicine using the Telegram app,…LRRK2 Mutation in a Patient with NMDA and GAD 65 Antibodies
Objective: To describe case of a patient who presented with a history of autoimmune encephalitis with NMDA receptor and GAD 65 antibodies positive in cerebrospinal…The Neuroprotective Effects of Rolipram, a Selective Phosphodiesterase IV Inhibitor, on Parkinson’s Disease in Rat Models: A Pharmacological Exploration in both In vivo and In vitro Settings
Objective: Our research sought to unravel the pharmacological effects and mechanisms of action of Rolipram through both in vivo and in vitro experimentation in models…Neuroprotective Efficacy of Ethanolic Extract from Amorphophallus Paeoniifolius Tuber Against Haloperidol-Induced Parkinson’s Disease Model
Objective: This study aimed to evaluate the neuroprotective and antiparkinsonian effects of the ethanolic extract of Amorphophallus paeoniifolius tuber (APT) against haloperidol-induced Parkinson’s Disease (PD)…
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