Beyond Parkinson’s Disease, Impulse Control Dysregulation: The Psychosocial Correlates of Problematic Internet Use
Objective: To determine the prevalence of problematic internet use and associated psychosocial correlates as a phenotype of impulse control dysregulation among undergraduates. Background: Impulse control…Iron-independent initiation of neurodegeneration in BPAN
Objective: Beta-propeller protein–associated neurodegeneration (BPAN) is caused by mutations in WDR45 and classified within the neurodegeneration with brain iron accumulation (NBIA) spectrum. Although brain iron…Manganese-induced neurotoxicity and Parkinsonian-like syndrome: potential protective role of Opuntia ficus-indica cladode extract in rats
Objective: The objective of this study was to evaluate the antioxidant and neuroprotective effects of an ethanolic extract of Opuntia ficus-indica cladodes against manganese-induced neurotoxicity…Three Different Behavioral Trajectories in L-DOPA–Treated Parkinson’s Disease Patients
Objective: To test the hypothesis that chronic pain may be associated with higher levodopa equivalent daily dosage (LEDD), and that patients who develop artistic creativity…Perceived Consequences and Catastrophising Help Explain Health-Related Quality of Life in Parkinson’s Disease
Objective: To examine if illness representations and cognitive-behavioural responses to symptoms explain additional variance in health-related quality of life (HRQoL) beyond demographic and established clinical…Fear Across the Disease Course: How Age, Sex, and Disease Duration Influence Different Types of Fear in Parkinson’s Disease
Objective: 1. To determine the prevalence of different fear types in people with Parkinson’s disease (PwP) and their perceived impact on daily activities. 2. To…Gelsolin and Secretogranin-3 induce Parkinsonian features in rodent models.
Objective: To study the pathogenic potential of Gelsolin (GSN) and Secretogranin-3 (SCG3) in inducing Parkinsonian features. Background: Parkinson’s disease (PD) is a complex neurodegenerative disorder…Suicidal Ideation and Behavior in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects both motor and non-motor neurological functions. In addition to motor impairment, patients frequently experience…The Protective role of Blood brain barrier-Vagal Interface in Parkinsonian pathology in mice
Objective: This study aimed to investigate whether vagal activity modulates BBB integrity and contributes to neurodegeneration and behavioral impairment in PD pathology. Background: Disruption of…Exploring Visual Scanning Behavior and Novelty Seeking in Parkinson’s Disease: A Pilot Study
Objective: To assess the feasibility of eye-tracking metrics in a Visual Paired Comparison (VPC) task as biomarkers for impulsivity in Parkinson's disease (PD) and to…
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