Identification of modifiers of the age of onset variance and disease progression in a Dutch cohort of Machado-Joseph disease patients
Objective: In this project, we aim to establish correlations between the length of the CAGexp, AO, and disease progression based on International Cooperative Ataxia Rating…Parkinson’s disease motor symptoms are linked to red nucleus volume and cerebellar metabolism
Objective: To investigate the involvement of the red nucleus (RN) and cerebellum in the motor symptoms of Parkinson's disease (PD). Background: Numerous studies have shown…Gluten sensitivity in progressive cerebellar ataxia patients from India
Objective: To screened a well-defined cohort of patients with cerebellar ataxia for the presence of gluten sensitivity. Background: Cerebellar ataxia is a heterogeneous group of…Abnormal Functional Connectivity in Cerebellar Locomotor Region is associated with the severity of freezing of gait in patients with Parkinson’s disease
Objective: We aim to analyze cerebellar functional connectivity (FC) in PD patients with FOG (PD-FOG). Background: Freezing of gait (FOG) is a disabling disorder frequently…Dissociative effects of thyrotropin releasing hormone on classical cerebellar ataxic signs and cerebellar adaptation in patients with spinocerebellar degeneration
Objective: To reveal effects of TRH [Thyrotropin releasing hormone (protirelin tartrate)] on the prism adaptation task in patients with spinocerebellar degeneration (SCD). Background: The cerebellum…Altered putamen and cerebellum connectivity between different subtypes of Parkinson’s disease
Objective: we investigate the functional connectivity (FC) patterns of the putamen between different subtypes of PD) and healthy controls, and explore its clinical significance. Background:…Slowly progressive anti-Ca/ARHGAP26 autoantibody-associated cerebellar ataxia over 27 years without immunosuppressive treatment
Objective: To discuss a slowly progressive case of anti-Ca/ARHGAP26 autoantibody-associated cerebellar ataxia. Background: Anti-Ca/ARHGAP26 autoantibody-associated cerebellar ataxia was first identified in 2010 (1). Since then,…Dopaminergic and Metabolic Imaging in Parkinson’s Disease motor subtypes and their relations to parkinsonian tremor
Objective: The mechanism underlying rest tremor of Parkinson’s disease(PD), while likely differing from those underlying akinesia and rigidity, remains unclear. The objective of this study…Under three seconds: Objective speech markers of ataxia in Multiple Sclerosis
Objective: To examine the relationship between objective markers of speech motor control, disease severity and ataxia. Background: Mild dysarthria is a common symptom of Multiple…The difference in cerebellar blood flow reduction in multiple system atrophy and Parkinson’s disease
Objective: The aim of this study is to determine if cerebral blood flow (CBF) reduction in the cerebellum could be a tool for differential diagnosis…
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