Neural Signals in the Cerebellar Nuclei Gate the Manifestation of Dystonia-Associated Symptoms in Mice
Objective: Define the differences in electrophysiological signatures of cerebellar output between mouse models of dystonia with diverse severity and manifestation. Background: Dystonia is heterogeneous movement…Deep gray matter atrophy in MSA subtypes
Objective: To compare MRI parameters of atrophy in Multiple system atrophy (MSA) subtypes. Background: MSA is a rare adult-onset synucleinopathology that can be divided in…Characterization of ataxia in Sjogren’s syndrome
Objective: This study aimed to characterize the pattern of ataxia in Sjogren’s syndrome and also to describe cerebellar ataxia and cerebellar atrophy in some of…Novel Mutation in the Protein Kinase C Gamma Gene Causing Spinocerebellar Ataxia-14 in a Large Family
Objective: To report a novel mutation not been previously reported in large, multi-ethnic general populations, in the protein kinase C gamma (PRKCG) gene causing spinocerebellar ataxia…Impulsivity and Compulsivity in Cerebellar Ataxias
Objective: To elucidate the role of human cerebellum in the reward processing system, of which a new cerebellar circuitry was recently identified in mice [1].…Tremor-dominant cervical dystonia and the cerebellum: lessons from saccade adaptation
Objective: To evaluate the role of the cerebellum in tremor-dominant cervical dystonia (CD) using a standardized saccade adaptation task. Background: While basal ganglia has long…Motor cerebellar connectivity and future development of freezing of gait in de novo Parkinson’s disease
Objective: To investigate the role of motor cerebellar connectivity in future development of freezing of gait (FoG) Background: Freezing of gait (FoG) in Parkinson’s disease…Resting State Functional and Structural Connectivity Changes of Cerebellum Basal Ganglia Interconnecting Network in Parkinson’s Disease
Objective: 1. Identify the role of Cerebellum Basal Ganglia structural and functional connectivity changes in Healthy subjects Vs PD patients. 2. Establish Cerebellum Basal Ganglia…Changes in the AKT/GSK3 pathway in the cerebellum increase susceptibility to movement disorders in a rat model of post-traumatic stress disorder
Objective: In an effort to investigate the role of PTSD in the aetiology of movement disorders, we assessed changes related to PTSD using the neurotrophic…Cerebellar structural covariance networks in young people with Tourette syndrome
Objective: To investigate discrete structural brain networks in children and adolescents with Tourette syndrome [TS] relative to a group of matched control participants. Background: TS…
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