MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Chorea (also see specific diagnoses, Huntingtons disease, etc): Treatment"

  • MDS Virtual Congress 2021

    Predictors of Persistence to Deutetrabenazine Among Patients With Tardive Dyskinesia (TD) and Huntington’s Disease (HD)

    D. Claassen, R. Ayyagari, V. Garcia-Horton, S. Zhang, S. Leo (Nashville, USA)

    Objective: To identify real-world predictors of persistence to deutetrabenazine in patients with TD or HD. Background: Deutetrabenazine is FDA-approved to treat TD in adults and…
  • MDS Virtual Congress 2021

    Evaluation of the QTc prolongation risk of deutetrabenazine

    F. Schneider, B. Darpo, M. Gutierrez, M. Gordon, L. Rabinovich-Guilatt (Ulm, Germany)

    Objective: To assess QTc prolongation risk of deutetrabenazine and its active metabolites by conducting exposure-QTc interval modeling, and to predict QTc prolongation in both CYP2D6…
  • MDS Virtual Congress 2021

    Proof-of-concept study testing bevantolol (SOM3355) as treatment of chorea in Huntington’s disease

    J. Gamez, M. Calopa, E. Muñoz, A. Ferré, O. Huertas, K. Mcallister, N. Reig, C. Scart-Grès, R. Insa, J. Kulisevsky (Barcelona, Spain)

    Objective: Proof-of-concept phase IIa study assessing bevantolol (SOM3355) efficacy and safety in reducing chorea in Huntington’s disease (HD). Background: Bevantolol hydrochloride, a β1‐adrenoceptor antagonist used…
  • MDS Virtual Congress 2021

    Diabetes Mellitus in Huntington’s disease. The Argentinean perspective

    N. Gonzalez Rojas, M. Cesarini, J. Etcheverry, E. Gatto (Buenos Aires, Argentina)

    Objective: to compare the prevalence of diabetes mellitus (DM) in a self-reported series of local Huntington disease (HD) participants in the ENROLL-HD registry with the…
  • MDS Virtual Congress 2021

    Characterizing US Healthcare Delivery in Huntington’s Disease (HD)

    L. Seeberger, J. Corey-Bloom, M. O'Brien, P. Chen, B. Griffin, D. Schlang, D. Slowiejko (Aurora, USA)

    Objective: The HD-Net research survey aimed to assess care patterns among practice types in the U.S., to identify gaps in the provision of HD care.…
  • MDS Virtual Congress 2021

    Healthcare utilization in individuals with late onset versus adult-onset Huntington’s disease

    J. Ta, TM. To, A. Patel, I. Abbass, S. Arndorfer, R. Ghandy (South San Francisco, USA)

    Objective: To assess healthcare utilization (HCU) among patients (pts) with late-onset Huntington’s disease (LoHD) versus adult-onset HD (AoHD) and non-HD controls. Background: HD typically manifests…
  • MDS Virtual Congress 2021

    Burden of illness among US Medicare beneficiaries with late-onset Huntington’s disease

    J. Ta, S. Reiss Reddy, E. Chang, A. Exuzides, R. Gandhy, G. Yohrling (South San Francisco, USA)

    Objective: Examine healthcare resource utilization (HRU) and costs among US Medicare beneficiaries with late-onset Huntington’s disease (LoHD). Background: Huntington’s disease (HD) is a genetic, neurodegenerative…
  • MDS Virtual Congress 2021

    Primary Palliative Care for Huntington Disease

    M. Harrison, D. Morrissey, F. Daly (Charlottesville, VA, USA)

    Objective: To develop a pilot program integrating primary palliative care with interdisciplinary care for Huntington disease (HD). Goals: 1) train HD team members to facilitate…
  • MDS Virtual Congress 2020

    Cytokines and Brain Specific Antibodies in Experimental Cellular and Molecular Treatment of Huntington’s Diseases

    D. Labunskiy, S. Kiryukhina, V. Podsevatkin (Saransk, Russian Federation)

    Objective: Huntington’s Disease (HD) is a severe neurodegenerative disorder main pathogenic factor is CAG repeats in a suffered patients genome. Experimental therapy on the model…
  • MDS Virtual Congress 2020

    A longitudinal PET study to assess the state of microglia activation in a Phase 2 study of Laquinimod as a treatment for Huntington’s disease (LEGATO-HD)

    A.A Roussakis, M. Gennaro, M.F Gordon, R. Reilmann, B. Borowsky, G. Rynkowski, J.M Savola, M.R Hayden, R. Gunn, S. Tabrizi, P. Piccini (London, United Kingdom)

    Objective: To assess in vivo in Huntington’s disease (HD) changes in microglia activation state, due to treatment with laquinimod, as reflected by changes in 11C-PBR28…
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