Schindler Disease (a Rare Autosomal Recessive Lysosomal Storage Disorder)
Objective: This case report discusses the diagnostic difficulties and treatment strategies for Schindler disease type III and provides insightful information on its clinical manifestations Background:…Phase I randomized, double-blind study to evaluate feasibility, safety, and clinical responses of implanting autologous peripheral nerve tissue into the nucleus basalis of Meynert or substantia nigra for non-motor or motor symptoms in patients with Parkinson’s disease undergoing DBS surgery (STAR) Trial
Objective: To evaluate the feasibility, safety, and clinical responses of bilateral delivery, at the time of deep brain stimulation (DBS) surgery, of autologous peripheral nerve…Modified Delphi consensus approach to develop recommendations for diagnosis, evaluation and management of cognitive disorders in Parkinson’s disease
Objective: We aimed to develop harmonised recommendations for the diagnosis, evaluation and management of cognitive disorders in PD using a modified Delphi process. Background: Differences…Changes in Cognitive Function with Deep Brain Stimulation in PD patients with and without Freezing of Gait
Objective: To determine if deep brain stimulation (DBS) changes cognitive function in Parkinson’s Disease (PD), and if these cognitive changes may relate to gait dysfunction…Orthostatic Hypotension and Acute Cognitive Dysfunction in Parkinson’s Disease: Insights from fNIRS
Objective: To define cerebral oxygenation changes during positional cognitive testing in Parkinson’s disease (PD), comparing those with orthostatic hypotension (OH+) to those without (OH-). Background:…Impaired Speech Perception in Noise (SPiN), Hearing Loss, and Cholinergic Denervation in Parkinson’s Disease
Objective: This study will investigate the relationships among speech-perception-in-noise (SPiN), hearing acuity, and cholinergic system changes in patients with PD. Background: Recent studies highlight a…Delirium following deep brain stimulation: An 8 year single-centre study
Objective: To describe the outcomes of patients undergoing deep brain stimulation (DBS) surgery for movement disorders and neuropsychiatric indications and characterise delirium symptoms. Background: Deep…Compound Heterozygous SCA17 in a Vietnamese Patient
Objective: We seek to report the first instance of Spinocerebellar Ataxia Type 17 (SCA17) in a Vietnamese patient with a compound heterozygous mutation in the…Multipronged, Community-Engaged Approach to Recruiting Lewy Body Dementia Family Caregivers for a National Trial
Objective: Describe a three-tiered initiative to recruit Lewy Body Dementia (LBD) family caregivers into a national randomized controlled trial (PERSEVERE, NCT06389032). Background: LBD is often…The East London Parkinson Disease Project: cultural fairness of common cognitive screening tests
Objective: The first objective of this work was to report the prevalence of Parkinson’s disease (PD) cognitive impairment in three ethnicities from the East London…
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