Cholinergic activity associates with cognitive function in PD using [18F]VAT
Objective: To map the relationship between cholinergic activity in Parkinson Disease (PD) and cognitive performance and identify any differences in this relationship in cognitive impairment.…Beyond Clinical Presentation: Incorporating Neuroimaging and Biofluid Markers to Predict Progression of Parkinson’s Disease
Objective: To assess whether including measurements of neuroimaging and biofluid-based biomarkers improves predictive ability of models of motor and non-motor progression up to 5-year follow-up…Predicting cognitive phenotypes in de novo Parkinson’s disease: an fMRI data-driven approach.
Objective: To verify whether connectivity changes in the dorsolateral prefrontal cortex (DLPC) and the precuneus (PCun) can predict cognitive phenotypes in de novo Parkinson’s disease…Frontal dysfunction as a cognitive biomarker in prodromal Parkinson’s disease
Objective: To assess specific cognitive biomarkers to increase the sensibility for the diagnosis of Prodromal Parkinson’s disease (pPD) that could help to identify these patients.…Apathy produces selective deficits in cognitive function when controlling for depression in patients with Parkinson’s disease
Objective: To compare differences in the mean cognitive impairment (CI) of patients with and without clinically significant apathy in PD, PD-mild cognitive impairment (PD-MCI), and…Parkinson’s Disease (PD) and predictors of Driving Cessation: Results from a 6-year Longitudinal Study and a systematic review of the literature
Objective: We sought to identify predictors of driving cessation among PD patients. Background: Motor and cognitive impairment of PD patients interfere with their driving ability.…The Contribution of APOE4 Genotype on Structural MRI in Parkinson’s Disease: A Study from the PPMI Cohort
Objective: To assess the contribution of Apolipoprotein E4 (APOE4) in Parkinson’s Disease (PD)-related cognitive impairment by analyzing its impact on Gray Matter Volume (GMV). Background:…Longitudinal Relationship Between Brain Metabolism and Clinical Changes in Huntington’s Disease
Objective: To understand the relationship between progression of the clinical symptoms and patterns of brain hypometabolism progression in a large cohort of Huntington’s disease (HD)…Early-onset Parkinsonism as Presenting Manifestation of CADASIL in a Mexican Woman with NOTCH3 c.1732C>T Pathogenic Variant
Objective: To report the case of a patient with parkinsonism as initial symptom, secondary to an specific NOTCH3 pathogenic variant.Objective: To report the case of…Assessment of cognitive impairment in Parkinson’s disease in under-represented ethnic groups-The London-Dhaka Parkinson’s Cognitive Study
Objective: The aim of this study is to evaluate the prevalence of CI in a diverse group of PwP from East London, UK and Dhaka,…
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