Basal forebrain contribution to cognitive deficits during medication “off” state in Parkinson’s disease
Objective: We sought to determine whether structural integrity of cholinergic Basal Forebrain (BF) was associated with subjective cognitive deficits experienced during medication “off” time Parkinson’s…Impact of the dopamine system on long-term, incident cognitive impairment in Parkinson disease
Objective: To determine the impact of the dopamine system (dopamine transporter [DAT] availability, dopamine-related SNPs, and dopaminergic medication use) on long-term cognitive performance in early…Boostering motor imagery processing to improve gait in patients with Parkinson disease and freezing of gait: a preliminary study
Objective: The aim of this study is to evaluate the priming effect of visual, auditory and cognitive tasks in enhancing Motor Imagery (MI) ability in…Huntington’s Disease, Cognition, and Fear of Falling
Objective: Explore the relationship of cognition and patient-reported assessment on fear of falling in people with Huntington’s Disease. Background: Huntington’s Disease (HD) is a relentlessly…Longitudinal predictors of functional dependence in a multicentric Parkinson’s Disease cohort
Objective: To explore clinical and cognitive predictors of functional dependence in a cohort of early Parkinson’s Disease (PD) patients. Background: Parkinson’s Disease (PD) patients are…A Useful Cognitive-Motor Dual Task Paradigm in Prodromal and Manifest HD
Objective: To investigate whether a cognitive-motor dual task (DT) paradigm uncovers deficits in balance in Huntington’s disease (HD) and, more importantly, prodromal HD, compared to…Late Onset Ataxia, Myoclonus, and Cognitive Decline in a Patient with Xeroderma Pigmentosum: A Case Report
Objective: To present a case of late onset neurologic symptoms of ataxia, myoclonus, and cognitive impairment in a 37-year-old man with xeroderma pigmentosum (XP). Background:…Influence of alcohol consumption on cognitive decline in Parkinson disease.
Objective: To assess whether alcohol consumption (AC) is independently associated with cognitive decline (CD) in PD. Background: AC is linked to dementia and neurological damage…Robust methods for missing covariates in longitudinal studies with application to biomarker research in Parkinson’s disease dementia
Objective: We propose a nonparametric method for handling different types of missing covariates in longitudinal studies. We show that the proposed method outperforms multiple standard…A randomized clinical trial (RCT) to evaluate the effects of safinamide on apathetic non-demented Parkinson’s disease patients
Objective: To evaluate the safety and effects of add-on safinamide on apathy in patients with Parkinson’s disease (PD). Background: Apathy is highly prevalent and disabling…
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