Impact of Cognition on Social Engagement in Community-based Older Adults with Parkinsonism
Objective: To investigate how cognition and gait influence social engagement in parkinsonism. Background: Social engagement is vital to quality of life in parkinsonism, yet the…A Qualitative Approach to Extract Diagnostic Patterns of Cognitive Impairment in Parkinson’s Disease
Objective: This study distilled patterns of patient performance recognized by clinical professionals in people with Parkinson’s disease (PD) and cognitive impairment on the Montreal Cognitive…Machine-learning Prediction of Cognition in Parkinson’s disease: Benchmarking EEG Source Functional Connectivity and Structural MRI
Objective: To develop machine-learning neural biomarkers to predict cognition in Parkinson’s disease (PD). Background: Variable levels of cognitive impairment are found in PD[1,2], but optimal…Approach into the genetics of cognitive performance in Mexican Parkinson’s Disease patients.
Objective: To compare the allele frequencies of genetic variants associated with cognitive impairment between Parkinson's Disease (PD) patients and controls and to examine their interaction…Decline in Motor Function and Cognitive Abilities in GBA PD Compared to Idiopathic PD (iPD)
Objective: To compare disease progression events between GBA PD and iPD using the Parkinson’s Progression Markers Initiative (PPMI) database Background: GBA PD patients exhibit more…The Role of Polygenic Background and APOE E4 in Monogenic and Idiopathic Parkinson’s Disease
Objective: To assess the impact of 1) polygenic risk scores (PRS) on monogenic Parkinson’s disease (PD) risk and time to diagnosis and 2) APOE E4…Medication Administration Burden in Lewy Body Dementia Caregivers
Objective: To evaluate medication administration burden among Lewy Body Dementia (LBD) family caregivers and associations with caregiver and care recipient characteristics. Background: Family caregivers of…A Randomized Clinical Trial of Immersive Virtual Reality and Cognitive Rehabilitation for Mild Cognitive Impairment in Parkinson’s Disease
Objective: To investigate the efficacy of Immersive Virtual Reality (IVR) and Computerized Cognitive Training (CCT) for mild cognitive impairment in Parkinson’s disease (PD-MCI) Background: PD-MCI…Determinants of Cognitive Progression in Parkinson’s Disease: A Machine Learning Approach
Objective: To identify clinical and sociodemographic factors associated with cognitive decline (CD) in PD using a Random Forests model, classifying people with PD (PwP) into…Baseline cerebrospinal levels of p-tau and amyloid beta and striatal dopamine transporter binding predict mild cognitive impairment and dementia diagnosis in Parkinson’s disease
Objective: To assess whether baseline measurements of neuroimaging and biofluid-based biomarkers predict diagnosis of mild cognitive impairment (MCI) and dementia at 5-year follow-up in early…
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