Seeking regulatory feedback on novel clinical outcome assessments: a case example from the Huntington’s Disease – Regulatory Science Consortium (HD-RSC)
Objective: To align with regulators on the utility and development strategy of novel clinical outcome assessments for use in Huntington’s disease (HD) clinical trials. Background:…Efficacy of Motor Imagery Questionnaire-RS as a Diagnostic Tool in Rehabilitation of Movement Disorders
Objective: The present study attempts to establish the normative reference value for motor imagery and compare it with patients with movement disorders. Background: Motor imagery,…Cognitive event related potentials as biomarker of non-motor phenotypes in Parkinson’s Disease
Objective: This research aimed to study the specific changes in cognitive event related potentials (ERP) in patients with different non-motor subtypes of Parkinson’s disease (PD).…Puzzle resolution as cognitive test in Parkinson´s disease patients
Objective: To analyze the value of puzzle resolution for cognitive testing in Parkinson´s disease patients. Background: Cognitive decline and dementia are common among Parkinson disease…The Effects of Time-Varying Caloric Vestibular Stimulation Therapy on Cognition Impairment in Parkinson’s Disease
Objective: To evaluate the potential efficacy of a software-controlled, solid-state, time-varying caloric vestibular stimulation (tvCVS) device for the treatment of cognitive impairment in Parkinson’s disease…Resting-state EEG spectral power in Parkinson’s disease
Objective: To examine the relationship between spectral power of resting state EEG (rsEEG) and cognition in Parkinson’s disease (PD). Background: Alzheimer patients have reduced rsEEG…Correlation between striatal CIT uptake and Mini-Mental State Examination in Parkinson’s disease
Objective: This study was performed to identify any relationship between the amount of decline of receptor uptake of CIT and Mini-Mental State Examination(MMSE) score in…DBS for Parkinson-Dementia syndrome: Stimulation of both Globus Pallidus internus & the Nucleus Basalis of Meynert using the same electrode lead
Objective: The study proposed a new Deep Brain Stimulation (DBS) approach in Parkinson´s disease (PD): the Globus pallidus pars interna (GPi) + Nucleus Basalis of…Neurocognitive changes after STN-DBS among PD patients – a 2-year follow-up study in Hong Kong
Objective: The study aimed to examine the neurocognitive changes following STN-DBS in patients with PD. Background: Neurocognitive evaluation is a standard procedure preoperatively in patients…Cognitive Inhibitory Control and Response to Dopaminergic Medication in Parkinson’s Disease
Objective: To investigate whether response to dopaminergic medication (DM) correlates to inhibitory cognitive control (IC) in patients with Parkinson's disease (PD). Background: In the MDS…
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