MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "COMT inhibitors"

  • MDS Virtual Congress 2020

    Opicapone in Parkinson’s disease – a centre’s real-life experience

    F. Carvalho, J. Silva, J. Araújo, M. Rodrigues (Braga, Portugal)

    Objective: To evaluate the therapeutic benefits, safety and tolerability of opicapone in a centre’s clinical practice. Background: Opicapone is a recent treatment for motor fluctuations…
  • MDS Virtual Congress 2020

    Efficacy and Safety of Opicapone in Parkinson’s Disease Patients According to Duration of Motor Fluctuations: Post-Hoc Analysis of BIPARK-I and II

    G. Ebersbach, O. Rascol, J. Ferreira, R. Costa, J.F Rocha, D. Magalhães, P. Soares-da-Silva (Beelitz, Germany)

    Objective: This exploratory post-hoc analysis evaluated the efficacy and safety of opicapone (OPC) in levodopa-treated Parkinson’s disease (PD) patients with duration of motor fluctuations of…
  • MDS Virtual Congress 2020

    Opicapone’s added benefit as a first-line adjunctive therapy to levodopa and when used promptly in the motor fluctuations spectrum of Parkinson’s disease: a post-hoc analysis of BIPARK-I and II

    G. Ebersbach, J. Ferreira, A. Antonini, A.T Santos, D. Magalhães, J.F Rocha, P. Soares-da-Silva (Beelitz, Germany)

    Objective: To evaluate opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuations according to disease- and therapy-related characteristics. Background: OPC, a once-daily catechol-O-methyltransferase inhibitor,…
  • MDS Virtual Congress 2020

    Efficacy of opicapone compared to entacapone in catechol-O-methyltransferase inhibitor-naïve Parkinson’s disease patients recently diagnosed with motor fluctuations: A post-hoc conservative analysis

    J. Ferreira, A. Lees, G. Ebersbach, A.T Santos, D. Magalhães, J.F Rocha, P. Soares-da-Silva (Lisbon, Portugal)

    Objective: To assess the efficacy of opicapone 50 mg (OPC 50 mg), compared with entacapone (ENT), in catechol-O-methyltransferase inhibitor (COMTi)-naïve Parkinson’s disease (PD) patients recently…
  • MDS Virtual Congress 2020

    Opicapone as First-Line Adjunctive Levodopa Treatment in Parkinson’s Disease Patients with Motor Fluctuations: Findings from BIPARK-I and II Combined Post-Hoc Analysis

    J. Ferreira, W. Poewe, A. Antonini, H. Gama, J.F Rocha, D. Magalhães, P. Soares-da-Silva (Lisbon, Portugal)

    Objective: This exploratory post-hoc analysis evaluated the efficacy and safety of opicapone (OPC) as first-line adjunctive therapy in levodopa/DOPA decarboxylase inhibitors-treated Parkinson’s disease (PD) patients…
  • MDS Virtual Congress 2020

    Efficacy and tolerability of opicapone in Parkinson´s disease in usual clinical practice

    V. Gomez-Mayordomo, F. Alonso-Frech, E. Lopez-Valdes, R. Garcia-Ramos, M. Catalan-Alonso (Madrid, Spain)

    Objective: To evaluate the efficacy and tolerability of opicapone in usual clinical practice in patients with Parkinson's disease (PD). Background: Opicapone is a recently approved…
  • 2019 International Congress

    Influence of disease severity in the efficacy response of Parkinson’s disease patients with motor fluctuations: post-hoc analysis from combined BIPARK-I and II

    H. Gama, A. Lees, J. Ferreira, O. Rascol, A. Antonini, A. Santos, D. Magalhães, J. Rocha, P. Soares-da-Silva (Coronado, Portugal)

    Objective: To evaluate the impact of disease severity on the efficacy of opicapone (OPC) in levodopa-treated Parkinson’s disease (PD) patients with motor fluctuations. Background: OPC,…
  • 2019 International Congress

    Addition of Opicapone to Safinamide in Parkinson’s Disease patients

    M. Russo, C. Carrarini, F. Dono, M. Di Pietro, M. Rispoli, L. Ferri, M. Onofrj (Chieti, Italy)

    Objective: To assess safety and efficacy of Opicapone in patients treated with Levodopa and Safinamide presenting early morning “off” states and akinesia. Background: Safinamide is…
  • 2019 International Congress

    Opicapone as a levodopa sparing agent: pooled analysis of BIPARK-I and II double-blind trials

    R. Hauser, O. Rascol, W. Poewe, J. Ferreira, A. Lees, O. Klepitskaya, G. Liang, A. Santos, D. Magalhães, J. Rocha, P. Soares-da-Silva (Tampa, FL, USA)

    Objective: To evaluate, in levodopa-treated Parkinson’s Disease (PD) patients, the ability of opicapone (OPC) to act as levodopa-sparing agent. Background: OPC, a once-daily COMT inhibitor,…
  • 2019 International Congress

    Influence of demographic characteristics in the efficacy response of Parkinson’s disease patients with motor fluctuations: post-hoc analysis from combined BIPARK-I and II.

    A. Santos, J. Ferreira, A. Lees, H. Reichmann, W. Poewe, F. Ikedo, D. Magalhães, J. Rocha, P. Soares-da-Silva (Coronado, Portugal)

    Objective: To evaluate the impact of demographic characteristics in the efficacy response of levodopa-treated Parkinson’s Disease (PD) patients with motor fluctuations. Background: Opicapone (OPC), a…
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