Prospective Tractography-Guided STN DBS Targeting with Optimized vmPFC Connectivity for Apathy in PD a Case Report
Objective: Prospective tractography-guided DBS targeting of the left STN-vmPFC and primary motor pathway to improve apathy alongside motor symptoms in PD. Background: While STN DBS…Multiple Independent Current Control for Gait Disorders in Early Programming of Parkinson’s Disease
Objective: To investigate the effect of Multiple Independent Current Control (MICC) on gait of Parkinson’s Disease (PD) Background: Classical programming with the ring and segmented…Clinical Efficacy of a Novel Deep Brain Stimulation System with 16-contact Directional Leads for the Treatment of Parkinson’s Disease
Objective: To examine the effectiveness of a Deep Brain Stimulation (DBS) system with 16-contact Directional Leads for the treatment of Parkinson’s Disease (PD). Background: Directional…A Retrospective, Multicenter, Harmonized Data Collection for Uncovering DBS Long-Term Axial Response
Objective: To determine pre-surgery (e.g., motor phenotype), during-surgery (e.g., electrodes' position), and post-surgery (e.g., stimulation parameters) factors predicting DBS-induced effects on axial symptoms in people…The Impact of Bilateral GPi Deep Brain Stimulation on Non-Motor Symptoms in Parkinson’s Disease
Objective: This study aimed to evaluate how bilateral Globus Pallidus internus (GPi) Deep Brain Stimulation (DBS) affects non-motor symptoms in individuals diagnosed with Parkinson’s disease…Towards automated deep brain stimulation programming using neurophysiology and artificial intelligence
Objective: To develop a machine learning (ML) algorithm capable of predicting the optimal deep brain stimulation (DBS) contact based on neurophysiology. Background: DBS is an…Bilateral Pallidal Deep Brain Stimulation in Secondary Dystonia in Louis-Bar-Syndrome Patients – A Report of Two Cases-
Objective: Deep Brain Stimulation (DBS) is an established treatment for various movement disorders, including primary dystonia. The effect in secondary dystonia is less well studied.…Tracking Physiological Biomarker Activity in the Globus Pallidus Internus in Two Dystonia Patients Implanted with Medtronic Percept™
Objective: Explore potential biomarkers in dystonia patients implanted with Medtronic Percept™. Background: Though highly variable in presentation and underlying cause, individuals with dystonia present with…Validating Real-World Evidence for Identifying Adverse Events Related to a Deep Brain Stimulation Implant
Objective: This study aims to validate Real-world evidence (RWE) using claims-based algorithms to identify adverse events (AEs) among patients implanted with a Deep Brain Stimulation…Cognitive Load Modulates Excitability of Subthalamic Motor Circuitry in Parkinson’s Disease
Objective: To characterize the effect of cognitive load on the excitability of circuitry connected with the subthalamic nucleus (STN) motor territory in Parkinson’s disease (PD)…
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