DIRECT DBS: A Prospective, Multicenter Clinical Study with Double-Blinding for a Directional Deep Brain Stimulation Lead – Visualization of Optimal Directionally Stimulated Anatomy
Objective: To visualize the volumes of activated tissue in relation to the neuroanatomy for the optimal stimulation parameters in Ring Mode (omnidirectional) stimulation in comparison…Frequency-dependent effects of subthalamic deep brain stimulation on motor symptoms in Parkinson’s disease
Objective: This study aims to investigate whether low-frequency stimulation (LFS) (100Hz, mostly 130 or 150 Hz) in deep brain stimulation (DBS) targeting subthalamic nucleus (STN).…The effectiveness of deep brain stimulation in dystonia: A patient-centered approach
Objective: To systematically evaluate the effectiveness of deep brain stimulation of the Globus Pallidus internus (GPi-DBS) in dystonia on pre-operatively set functional priorities in daily…An Objective Tool to Guide Target Selection for DBS in PD (GPi vs STN) – integration into Thomas Jefferson’s multidisciplinary Movement Disorders Center
Objective: After the creation of simple tool to aid in selection of the proper target for Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD), our…Swimming in PD patients with STN-DBS: A pilot exploratory study
Objective: Patients with PD frequently complain of losing abilitiy to swim. Our aim was to test the swimming abilities of our patients with bilateral STN-DBS…Simple Programming Method in STN-DBS using directional lead
Objective: Consider a stimulation programming method that can be performed easily and in a short time. Background: Background: Since the subthalamic nucleus (STN) is a…Symptom specified target and procedure selection for Parkinson’s disease: A case report
Objective: To examine the clinical benefits and side effects of combined stereotactic surgery, namely ventralis intermedius (VIM) thalamotomy and bilateral asymmetric GPi/STN DBS, for Parkinson's…Long-term Outcomes with Rescue Target Deep Brain Stimulation in Patients with Dystonia
Objective: Determine the long-term outcomes of rescue target deep brain stimulation (DBS) surgery in dystonia. Background: Globus pallidus internus (GPi) and subthalamic nucleus (STN) are…The effect of thalamic and subthalamic deep brain stimulation on speech in patients with essential tremor: A prospective, randomized, double-blind crossover study
Objective: To investigate the effect of thalamic (ventral intermediate nucleus, VIM) and subthalamic (posterior subthalamic area, PSA) deep brain stimulation (DBS) in patients with essential…Cerebrospinal fluid protein biomarkers in PD patients after DBS-STN surgery: A retrospective analysis of patients that underwent surgery between 1993 and 2001
Objective: To investigate cerebrospinal fluid (CSF) markers of neurodegeneration [neurofilament light chain (NFL), total Tau (T-Tau)], tau pathology [phosphorylated tau (p-Tau)], glial cell damage or…
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