Non-Motor Symptom Improvement as a Driver of Quality of Life after Subthalamic Stimulation in Symmetric Parkinson’s Disease
Objective: To investigate non-motor outcomes in patients with symmetric vs. asymmetric motor symptoms following subthalamic stimulation (STN-DBS) in Parkinson’s disease (PD). Background: Motor asymmetry is…Functional Improvement Following Early GPi-DBS for Moderate-Stage Atypical KMT2B Dystonia: A Case Report in a 13-Year-Old Girl
Objective: To report clinical trajectory and functional improvement of a child with atypical KMT2B-related dystonia following bilateral GPi-DBS performed at a moderate disease stage. Background:…When Surgical Candidates Become Ineligible: Loss of Deep Brain Stimulation Eligibility in Parkinson’s Disease — A Descriptive Study from a Brazilian Referral Center
Objective: To describe the clinical and non-clinical reasons leading to loss of surgical eligibility among patients initially considered candidates for Deep Brain Stimulation (DBS) in…Clinical impact of local field potential sensing–guided deep brain stimulation: a real‑world registry
Objective: To evaluate the association between Local Field Potential (LFP) sensing use and patient outcomes (EuroQol 5-Dimensions (EQ5D), medications), as well as device-related outcomes by…Ecological Momentary Assessment Monitoring Captures Motor Fluctuation Improvement after DBS in Parkinson’s Disease
Objective: To evaluate whether mobility measures based on ecological momentary assessment (EMAs) capture deep brain stimulation (DBS) motor improvement in Parkinson’s disease (PD) and correlate with clinician-rated motor impairment (UPDRS III) and motor…Chinese Expert Consensus and Recommendations on Sensing-guided Deep Brain Stimulation for Parkinson’s Disease: A Modified Delphi Study
Objective: To propose some well-accepted recommendations on sensing-guided deep brain stimulation for Parkinson's Disease. Background: Deep brain stimulation (DBS) has been widely accepted as a well-established neurosurgical…Anatomical and electrical field determinants of axial motor outcome after bilateral GPi-DBS in Parkinson’s disease
Objective: To determine anatomical and electrical field parameters associated with short-term improvement in axial motor scores after bilateral GPi-DBS in PD. Background: Axial symptoms in…Randomized Controlled Trial Comparing Adaptive versus Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease; Closed Loop Optimization of Deep Brain Stimulation Effect in Parkinson’s Disease (CLOSE-PD study)
Objective: To evaluate whether adaptive deep brain stimulation (aDBS) of the subthalamic nucleus (STN) is more efficacious than continuous DBS (cDBS) in Parkinson's disease (PD)…The UF Adaptive Deep Brain Stimulation Experience
Objective: To describe our single center experience with implementing adaptive deep brain stimulation (aDBS) strategies into a high-volume neuromodulation center. Background: Adaptive deep brain stimulation…Clinical Outcomes of Globus Pallidus Interna Deep Brain Stimulation in Primary and Secondary Dystonia: A Single-Center Experience
Objective: To evaluate motor and disability outcomes following GPi-DBS in a mixed cohort of primary and secondary dystonia patients treated from a tertiary referral center…
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