Movement decoding from subthalamic nucleus during deep brain stimulation surgery
Objective: To evaluate motor classification and somatotopy of local field potentials (LFPs) recorded from subthalamic nucleus (STN) directional deep brain stimulation (DBS) electrodes. Background: STN…Axial parkinsonism after 15 years of pallidal stimulation in generalized dystonia
Objective: To characterize long-term motor outcomes and emergence of parkinsonian symptoms after 15 years of bilateral globus pallidus internus deep brain stimulation (GPi-DBS) in isolated…Burst versus Conventional Deep Brain Stimulation Engage Distinct Cortico-Subthalamic Circuit Dynamics in Parkinson’s Disease
Objective: To characterize the neural effects of burst DBS (bDBS) on cortico-subthalamic circuit dynamics in Parkinson’s disease (PD) and determine whether they differ from conventional…Verbal Communication After Subthalamic Nucleus Deep Brain Stimulation
Objective: To evaluate the contribution of motor speech, language, and cognition to communication changes after subthalamic nucleus deep brain stimulation (STN-DBS) in people with Parkinson’s…DBS withdrawal syndrome in Parkinson’s disease: Clinical features and outcomes of two new cases
Objective: To report two cases of deep brain stimulation (DBS) withdrawal syndrome in Parkinson’s disease (PD), including one without typical risk factors. Background: DBS withdrawal…Lead Asymmetry and Axial Symptom Response to Deep Brain Stimulation in Parkinson’s Disease: A Synthetic Pilot Modeling Study
Objective: To evaluate whether bilateral DBS lead placement asymmetry captures clinically meaningful correlates of motor outcomes, particularly freezing of gait (FoG) and balance to establish…Structural Brain Measures Predict Cognitive Performance After Deep Brain Stimulation for Parkinson’s Disease
Objective: To determine whether pre-operative brain morphometry, combined with baseline neuropsychological performance, can predict post-operative cognitive performance in PD patients undergoing DBS using a sparse…Event-Locked Characterization of Movement-Related Beta Modulation using Synchronized Local Field Potentials and Video-Based Kinematics
Objective: Identifying physiomarkers of PD motor function beyond total beta power by examining event-related subthalamic nucleus beta modulation during continuous finger tapping (FT) using synchronized…A case of difficulty extubating after General Anesthesia Deep Brain Stimulation (DBS) surgery
Objective: Dysfunction in speech, respiration, and swallowing can severely compromise the well-being of Parkinson’s disease (PD) patients. Here, we present a rare case of acute…An Optimized Workflow for High-Throughput RNA-Seq from Human Deep Brain Tissue Using DBS Microelectrodes
Objective: To optimize a workflow for extracting human deep brain RNA from DBS microelectrodes for transcriptome sequencing. Background: Understanding the molecular mechanisms of Parkinson’s disease…
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