Modulation of Finely Tuned Gamma in the Globus Pallidus Internus with Deep Brain Stimulation and Levodopa
Objective: To characterize narrow band gamma and finely tuned gamma (FTG) in the globus pallidus internus (GPi) in patients with Parkinson’s disease (PD) and the…Beyond the “best contact”: correlation of ai-guided dbs contact distribution and subthalamic nucleus beta physiology in parkinson’s disease patients
Objective: We hypothesized that optimal stimulation setting may involve a muti-contact configuration rather than a single contact with the largest therapeutic window (TW). We aimed…Clinical Features of DJ1 Gene Mutation Causing Parkinson’s Disease from a Single Centre
Objective: Describe the detailed clinical characteristics of patients diagnosed with Parkinson’s disease (PD) who have the DJ1 gene mutation. Background: Inherited PD represents 5-10% of…Optogenetic mediated inhibition of the subthalamic nucleus alleviates motor symptoms in experimental hemi-parkinsonism mouse model
Objective: Study the potential of optogenetic suppression of STN neurons in alleviating motor symptoms in a PD mouse model using the novel inhibitory opsin eOPN3.…Prediction of Cognitive Decline After STN-DBS in Parkinson’s Disease Using Preoperative Electroencephalography and a Deep Learning Model
Objective: To determine whether preoperative electroencephalography (EEG) combined with deep learning can predict cognitive decline 1 year after subthalamic deep brain stimulation (STN-DBS) in patients…Movement decoding from subthalamic nucleus during deep brain stimulation surgery
Objective: To evaluate motor classification and somatotopy of local field potentials (LFPs) recorded from subthalamic nucleus (STN) directional deep brain stimulation (DBS) electrodes. Background: STN…Axial parkinsonism after 15 years of pallidal stimulation in generalized dystonia
Objective: To characterize long-term motor outcomes and emergence of parkinsonian symptoms after 15 years of bilateral globus pallidus internus deep brain stimulation (GPi-DBS) in isolated…Burst versus Conventional Deep Brain Stimulation Engage Distinct Cortico-Subthalamic Circuit Dynamics in Parkinson’s Disease
Objective: To characterize the neural effects of burst DBS (bDBS) on cortico-subthalamic circuit dynamics in Parkinson’s disease (PD) and determine whether they differ from conventional…Verbal Communication After Subthalamic Nucleus Deep Brain Stimulation
Objective: To evaluate the contribution of motor speech, language, and cognition to communication changes after subthalamic nucleus deep brain stimulation (STN-DBS) in people with Parkinson’s…DBS withdrawal syndrome in Parkinson’s disease: Clinical features and outcomes of two new cases
Objective: To report two cases of deep brain stimulation (DBS) withdrawal syndrome in Parkinson’s disease (PD), including one without typical risk factors. Background: DBS withdrawal…
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