Cognitive Profile In Indian Patients with Spinocerebellar Ataxia (SCA) – Prospective Cross-sectional Study
Objective: To evaluate the prevalence, spectrum, and severity of cognitive impairment in Indian patients with genetically confirmed SCA and corelate with motor severity. Background: Beyond…Differences in Lewy body dementia in people from ethnic minorities: a systematic review of epidemiology, diagnosis, clinical features and imaging
Objective: To systematically review evidence on epidemiological and clinical differences in Lewy body dementia (LBD), including dementia with Lewy bodies (DLB) and Parkinson’s disease dementia…[18F]-FDG-PET metabolic phenotyping in idiopathic normal pressure hydrocephalus: visual and voxel-wise evidence across neurodegenerative phenotypes
Objective: To characterise FDG-PET metabolic phenotypes in idiopathic normal pressure hydrocephalus (iNPH) using integrated visual and voxel-wise analyses. Background: iNPH is a potentially treatable cause…A Novel Case of Persistent Singing in Progressive Supranuclear Palsy
Objective: To present a unique case of a person with progressive supranuclear palsy (PSP) who developed persistent singing, and review the relevant literature. Background: Persistent…Risk stratification study of fluid biomarkers for alpha-synucleinopathy with dementia
Objective: This study focuses on mixed pathology of α-synucleinopathy and Alzheimer’s disease(AD), analyzing the relationships among biomarkers, genetic factors, and cognitive function in order to…Data-driven Longitudinal Trajectories of Hippocampal Volume in Parkinson’s Disease and Across the Neurodegenerative Disease Spectrum
Objective: To elucidate hippocampal (HP) volume trajectories in Parkinson disease (PD) and across the neurodegenerative disease (NDD) spectrum. Background: HP volume is a critical neuroimaging…Optimizing Institutional Long-Term Care in Advanced Parkinson’s and Other Neurodegenerative Disease: The OPTICARE Study
Objective: To analyze and improve institutional long-term care (LTC) structures for patients with advanced PD and AD by identifying modifiable determinants of care integration, QoL,…The Burden of Cognitive Impairment in People with Parkinson’s across Outpatients and Prevalent Patients in Coastal Kenya: A Transforming Parkinson’s Care in Africa (TraPCAf) Study
Objective: To describe the rate and severity of cognitive impairment within the coastal Kenyan cohort of TraPCAf. Background: Cognitive impairment is a well-recognised non-motor symptom of PD, however there is very…Spatiotemporal Trajectories of Plasma Biomarkers and Diffusion MRI Metrics in Parkinson’s Disease
Objective: To investigate the spatiotemporal dynamics of multimodal biomarkers and their role in early prediction of cognitive decline. Background: Cognitive impairment is a major source…Investigating the Link Between Alzheimer’s Disease Genetic Risk Variants and Parkinson’s Disease Cognitive Impairment: An Exploration of Genetic Overlap
Objective: To investigate whether variants from a large Alzheimer’s disease (AD) genome-wide association study (GWAS; Bellenguez et al. 2022) in Europeans - including 85,934 clinically…
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