Role of ApoE in α-Synuclein Pathology
Objective: To investigate whether apolipoprotein E (ApoE) isoforms directly interact with α-synuclein and determine how these interactions influence aggregation dynamics and cellular uptake. Background: The…A Switching from Oral Donepezil to a Twice-Weekly Korean Transdermal Donepezil Patch in Patients with Dementia with PD
Objective: Aimed to assess caregivers’ satisfaction with and preference for a transdermal donepezil patch compared with conventional oral formulations in patients with d-PD, with the…The Clinical and Neuropathological Factors Associated with Brain Atrophy in CSF1R-RD.
Objective: To characterize the clinical and neuropathological factors associated with brain atrophy in CSF1R-related disorder (CSF1R-RD). Background: CSF1R-RD is a rare, fatal autosomal dominant leukoencephalopathy…Raman Spectroscopic Identification of Biochemical Alterations in Post Mortem Brain Tissue Microarrays from Parkinsons and Alzheimers Disease
Objective: To investigate biochemical differences in neuronal, vascular and neuropil regions of post mortem brain tissue from Parkinsons disease and Alzheimers disease using Raman microscopy.…Predicting Dementia in Parkinson’s Disease Using Blood-Based Proteomics
Objective: To identify a proteomic profile associated with the future development of dementia in recently diagnosed Parkinson’s disease (PD) patients. Background: Dementia is a common…Strategies for Harmonising Clinical Data for Multi-Centre, Large Scale Genome-Wide Association Studies
Objective: To establish a data harmonisation framework for classifying cognitive status in Parkinson’s disease (PD) across multiple study and data types to facilitate large-scale genetic…Multivariate Cognitive Markers of Dementia Progression in Parkinson’s Disease
Objective: To identify neuropsychological markers at the PD-MCI stage associated with the progression severity to PDD using a multivariate, data-driven approach with longitudinal validation. Background:…Neuropsychiatric Symptoms in Lewy Body Disease: Monoaminergic Activity and Resting State Networks
Objective: Investigating how neuropsychiatric symptoms (NPS)—depression, anxiety, and apathy—relate to functional connectivity between monoaminergic nuclei and the limbic network (LN), default mode network (DMN), and…Machine Learning for Early Detection of Huntington’s Disease: Integrating Non-Motor Symptoms and Gender-Specific Differences
Objective: To develop a machine learning (ML) model for early Huntington’s disease (HD) detection by integrating non-motor symptoms (NMS) and DNA methylation patterns, leveraging gender-specific…Bidirectional associations between seizures and parkinsonism: a retrospective case series
Objective: Within a single center, describe individuals with parkinsonism who develop seizures and vice versa based on epilepsy and movement disorders evaluation. Background: While neurodegeneration…
- 1
- 2
- 3
- …
- 39
- Next Page »