Effects of zonisamide on parkinsonism in patients with dementia with Lewy bodies by severity of cognitive dysfunction and BPSD: subgroup analysis of pooled data from two trials
Objective: To characterize the efficacy and safety of zonisamide (ZNS) in patients with dementia with Lewy bodies (DLB) with parkinsonism, we performed subgroup analysis by…Visual evoked potentials alterations in DLB
Objective: To investigate whether DLB and PD patients show VEP and OCT alterations in comparison with AD patients, and whether this possible alterations are associated…Preclinical profile of dopamine D1PAM: A novel mechanism in clinical development for Lewy Body dementia
Objective: Introduce the mechanism of action for dopamine D1 positive allosteric modulator (D1PAM) as a new target for neuropsychiatric disorders. Describe the preclinical profile of…Brain amyloid contribution to cognitive dysfunction in Lewy bodies disorders: a pilot study
Objective: To investigate regional [18F]florbetapir binding to amyloid-β and its contribution to cognitive dysfunction in Lewy bodies disorders. Background: Lewy bodies disorders like Parkinson’s disease…Functional exam findings in Lewy Body Disease
Objective: Case study to review functional exam findings in an abnormal Dopaminergic transporter scan positive Lewy body dementia patient. Background: Patient presented with known Parkinson’s…Clinical and neuroimaging heterogeneity of dementia with Lewy bodies
Objective: To study clinical and neuroimaging features of dementia with Lewy bodies (DLB) for optimal management and prognosis of the disease. Background: Appropriate diagnosis of DLB…Dementia with Lewy bodies: GBA1 mutations are associated with cerebrospinal fluid alpha-synuclein profile
Objective: Whether GBA1 mutations are associated with a CSF alpha-synuclein profile in DLB. Background: Patients with dementia with Lewy bodies (DLB) reveal a variable pathology…Impaired colour discrimination is associated with hallucinations in Dementia with Lewy Bodies
Objective: To explore the hypothesis that color discrimination impairment seen in Lewy body disorders is a specific biomarker of visual hallucinations rather than just overall…The role of LRP10 mutations in Parkinson’s Disease and Dementia with Lewy Bodies
Objective: To test LRP10 in a cohort of Italian patients, with a clinical diagnosis of either Parkinson’s Disease (PD) (n=316) or Dementia with Lewy Bodies…Differential temporal processing across Lewy body disorders and relation to cognitive fluctuations
Objective: To characterize differences in interval timing between patients with Parkinson’s disease and Dementia with Lewy bodies (DLB) and evaluate their relationship to cognitive fluctuations…
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