α-Synuclein propagation via olfactory pathway induces olfactory bulb atrophy and widespread glucose hypometabolism in a non-human primate model
Objective: We investigated how α-synuclein (α-Syn) pathology spreads from the olfactory bulb (OB) and how the pathology affects brain structure and activity. Background: Parkinson's disease…Magnetic Property Characterization of Deep Gray Matters in Patients with Alzheimer’s diseases, Dementia with Lewy Bodies and Parkinson’s Disease Dementia using Quantitative Susceptibility Mapping
Objective: The purpose of this study was to characterize magnetic properties of deep gray matters in Alzheimer's diseases (AD), dementia with Lewy bodies (DLB) and…A Lewy body disease of widely confirmed Lewy bodies in the cerebral cortexes including the occipital lobe without pathological changes in the hippocampal CA2/3 region
Objective: We present Lewy body disease (LBD) showing unique neuropathological findings which are widely recognized Lewy bodies (LBs) in the cerebral cortexes including the occipital…Visual hallucinations in Lewy Body Disease are characterised by impaired sensory integration
Objective: To test whether increased reliance on prior knowledge is associated with visual hallucinations in Lewy Body Disease (LBD: Parkinson’s disease and Dementia with Lewy…Increased lysosphingolipids levels in blood of patients with multiple system atrophy
Objective: To estimate activity of lysosomal enzymes and lysosphingolipids concentration in dry blood spot of patients with synuleinopathies: Parkinson’s disease (PD), dementia with Lewy bodies…Patterns of Lewy body dementia diagnosis and treatment in Florida
Objective: To characterize the demographic and treatment characteristics for the Lewy body dementia (LBD) population in Florida using a statewide clinical data research network. Background:…The frequency and impact of mutations in the GBA gene and APOε4 polymorphisms on the clinical features of Dementia with Lewy Bodies among Ashkenazi Jews
Objective: We aimed to explore the frequency and clinical impact of GBA mutations and APOε4 polymorphisms in a cohort of Ashkenazi Jewish (AJ) patients with…Extrastriatal dopaminergic and serotonergic pathways in Parkinson’s disease and in dementia with Lewy bodies: a 123I-FP-CIT study
Objective: To evaluate the common and divergent dopaminergic and serotonergic impairment in Parkinson's disease and dementia with Lewy bodies using 123I-FP-CIT imaging. Background: Striatal dopaminergic…Alpha-synuclein expression and cytokine profile in blood of patients with Lewy body dementias
Objective: To examine alpha-synuclein expression in CD45+ and cytokine levels in blood of patients with dementia with Lewy bodies (DLB), Parkinson's disease dementia (PDD). Background:…New Neuropathological Staging System for Lewy Body Disease
Objective: Present the validation of the new proposed novel staging system (NSS) for Lewy body disease and compare it against the previously proposed staging systems. Background:…
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