Effects of white matter hyperintensities, neuropsychiatric symptoms, and cognition on activities of daily living: Differences between Dementia with Lewy Bodies and Alzheimer’s disease
Objective: To investigate if White matter hyperintensities (WMHs), neuropsychiatric symptoms and cognitive performance associate with, and/or predict activities of daily living (ADLs) differently in Alzheimer’s…Prevalence of Suicidal Ideation and Associated Clinical Features in Lewy Body Dementia
Objective: The goal of this study was to identify the prevalence of suicidal ideation (SI) in Lewy body dementia (LBD) and the factors associated with…Event-related oscillations in patients with Dementia with Lewy Bodies with and without mutations in the GBA gene
Objective: To explore the differences in the structure of event-related oscillations (ERO) elicited by a visual oddball task in Dementia with Lewy bodies (DLB) patients…Elucidating multimodal endophenotypes of APOE-ε4 in α-synucleinopathies
Objective: To systematically identify phenotypes that consistently associate with the ε4-allele of apolipoprotein E (APOE-ε4) in α-synucleinopathies. Background: The APOE-ε4 presents an elevated risk not…AMP PD: Collaborating in the discovery of biomarkers to accelerate the development of therapies for Parkinson’s disease
Objective: The Accelerating Medicines Partnership in Parkinson’s Disease (AMP PD; https://amp-pd.org) aims to identify and validate diagnostic, prognostic, and progression biomarkers for Parkinson’s Disease (PD).…Non-Tremor Motor Dysfunction is Associated with AD Biomarkers in Lewy Body Dementias
Objective: To investigate the clinical influence of Alzheimer’s disease (AD) co-pathology on motor features in Lewy Body Dementia (LBD). Background: There is considerable heterogeneity of…Analysis of the HLA locus in isolated REM sleep behavior disorder and Lewy body dementia
Objective: To examine genetic association of HLA alleles and amino acid for isolated REM sleep behavior disorder (iRBD) and Lewy body dementia (LBD). We compare…CHARACTERIZATION OF LRP10 EXPRESSION IN LEWY BODY DISORDERS AND IPSC-DERIVED BRAIN CELLS
Objective: Our objective is to characterize endogenous low-density lipoprotein-related protein 10 (LRP10) expression in human induced pluripotent stem cell (iPSC)-derived brain cell types, post-mortem brain…Predictors of the progression of dementia with Lewy bodies
Objective: To define predictors of the progression of dementia with Lewy bodies (DLB). Background: Dementia with Lewy bodies is a progressive disabling neurodegenerative disease with…Comparison of 123I-MIBG myocardial scintigraphy and 123I-FP-CIT SPECT between dementia with Lewy bodies and Parkinson’s disease
Objective: The objective of this study was to compare the nuclear medicine images of dementia with Lewy bodies (DLB) and Parkinson's disease (PD) patients and to extract findings…
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