Use of pimavanserin in patients with Parkinson’s disease psychosis: Subgroup analysis of efficacy and safety in patients with and without cognitive impairment
Objective: A planned subgroup analysis of a phase 3 study was performed to evaluate the efficacy and safety of pimavanserin (PIM) in Parkinson’s disease psychosis…Self-awareness of cognitive functions in Parkinson’s disease patients with and without mild cognitive impairment.
Objective: To examine whether Parkinson’s disease (PD) patients with or without mild cognitive impairment (MCI) show impaired self-awareness (ISA) of their cognitive abilities. Background: PD…Rationale and Design of a Phase 2 Study to Evaluate the Efficacy of Intepirdine (RVT-101) in Improving Gait and Balance in Patients with Dementia
Objective: To describe the rationale and design of a Phase 2 study that evaluates the effect of intepirdine (RVT-101) on gait and balance in patients…Clinicopathological analysis of corticobasal syndrome: a retrospective study
Objective: Predicting underlying pathology in CBS. Background: Corticobasal syndrome (CBS) is pathologically heterogeneous. CBS is one of the clinical phenotypes of corticobasal degeneration (CBD) but may…Risk Factors for Dementia in Parkinson’s disease
Objective: To investigate putative risk factors for the development of dementia in patients with Parkinson’s disease. Background: Dementia in idiopathic Parkinson’s disease (PD) is a…Oscillatory Activity in the Nucleus Basalis of Meynert
Objective: Characterize oscillatory activity in and around the nucleus basalis of Meynert (NBM). Background: The NBM is the major source of cholinergic innervation to the…Changing patterns of intimate relationships as dementia emerges in Parkinson’s disease
Objective: To explore relationship satisfaction and aspects of intimacy in female partners of people with cognitive impairment associated with Parkinson’s disease (PD) using qualitative methods.…Ghrelin and the IGF-1 axis in cognitive impairment in PD
Objective: To explore the association of acyl-ghrelin (AG) levels with cognitive impairment (CI) in PD Background: Unintended weight loss (UWL) in PD is associated with…Resting state modulations of EEG low frequency bands in Parkinson’s disease.
Objective: Dynamics in EEG activity such as slowing in low-frequency bands has been reported in Parkinson’s disease (PD). The objective of the present study was…Key clinical milestones 15 years and onwards after DBS-STN surgery – a retrospective analysis of patients that underwent surgery between 1993 and 2001
Objective: In this paper we investigated patients with advanced Parkinson's disease (PD) operated at our center with subthalamic nucleus deep brain stimulation (STN-DBS) for at…
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