Structural brain abnormalities associated with preclinical cognitive impairment in Idiopathic Parkinson’s Disease.
Objective: Using the Progressive Parkinson’s Initiative (PPMI) data, clinical and structural differences between individuals destined to develop PD cognitive impairment was defined. Background: Cognitive dysfunction…The battery longevity of implantable pulse generators (IPG) in Parkinson’s disease (PD) is affected by IPG model, number of previous IPG replacements and stimulation energy delivered.
Objective: To determine the effects of stimulation parameters, IPG model and the number of previous IPG replacements on IPG battery longevity. Background: For some patients rechargeable…Predictor of progressive mild cognitive impairment in patients with Parkinson’s disease.
Objective: To clarify clinical features of patients with progressive mild cognitive impairment patients (MCI) in Parkinson’s disease (PD-MCI). Background: Non-demented PD subjects have MCI and…Grey matter abnormalities associated with early cognitive decline in Parkinson’s disease
Objective: To identify patterns of grey matter (GM) abnormalities in patients with Parkinson's disease (PD) with different cognitive profiles. Background: Cognitive symptoms occur already in…Ataxia and increased cerebrospinal fluid phosphate associated with a mutation in the SLC20A2 gene
Objective: To characterize the phenotype and biochemical abnormalities associated with the R467X mutation in the SLCA20A2 gene. Background: Mutations in the SLC20A2 gene are the…Differential peculiarities of cognitive disorders in Parkinson’s disease dementia and Vascular dementia
Objective: To study differential peculiarities of cognitive functions disorders in Parkinson's disease (PD) dementia and vascular dementia (VD). Background: 44 VD and 18 PD dementia…Screening of cognitive impairment in Huntington’s disease with the Parkinson’s Disease – Cognitive Rating Scale (PD-CRS)
Objective: To explore the psychometric properties of the PD-CRS as compared to two commonly used measures (the MMSE and the UHDRS Cognitive score) for detecting…Multimodal biomarkers as predictors of cognitive decline in Parkinson’s Disease
Objective: To identify a set of multimodal biomarkers to predict cognitive decline in non-demented Parkinson’s disease patients. Background: People with Parkinson’s Disease are at high…“Essential tremor” as a presenting symptom of neuronal intranuclear inclusion disease (NIID).
Objective: To describe a patient with late onset, sporadic NIID who had a tremor as his first complaint. Background: NIID is a rare, slowly progressive…Plasma Biomarkers in Idiopathic Normal Pressure Hydrocephalus
Objective: (1) To investigate the role of plasma biomarkers that is known to related to Alzheimer’s disease in INPH(2) To assess the diagnostic and prognostic…
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