10 year longitudinal change in clinical and biological characteristics of sporadic Parkinson Disease PPMI cohort
Objective: To present data on 10 year longitudinal clinical and biological characteristics of sporadic Parkinson Disease (sPD) participants in the Parkinson’s Progression Markers Initiative (PPMI)…Sex differences for clinicopathological correlations in people with Lewy body pathology
Objective: To determine sex-specific clinical correlations of different Lewy body (LB), Alzheimer’s disease (AD) pathology staging and nigral neuron loss levels in people with LB…Creutzfeldt-Jakob Disease misdiagnosed as Corticobasal degeneration
Objective: We described clinical, radiologic, and neuropathological findings of a patient with Creutzfeldt-Jakob Disease who presented antemortem with clinical features suggestive of corticobasal degeneration. Background:…Extent of cognitive impairment in Parkinson`s disease with Covid-19
Objective: To study of the extent of cognitive impairment in PD patients with Covid-19. Background: Covid-19 may aggravate the clinical course of Parkinson's disease (PD)…Effect of Sex on the association between GBA mutations and Cognitive Decline in Parkinson’s Disease
Objective: To assess the impact of sex and glucocerebrosidase (GBA) mutations on cognitive trajectories in a sample of Parkinson's disease (PD) patients. Background: Accumulating evidence…Amyloid status differentiates synaptic loss and atrophy in Corticobasal Syndrome.
Objective: In this observational/cross-sectional study, we tested whether the degree and extent of in vivo synaptic loss differed in patients with corticobasal syndrome according to…Cholinergic deficits in Parkinson Disease
Objective: To determine whether loss of cholinergic projections to cortical and limbic regions contributes to the development of dementia in Parkinson’s disease (PD). Background: PD…Atypical parkinsonism and psychiatric disorder in hereditary diffuse leukoencephalopathy with spheroids: a novel variant in the CSF1R gene
Objective: We describe the clinical, radiological and neuropathological phenotype of a patient carrying a novel variant in the CSF1R gene. Background: Hereditary diffuse leukoencephalopathy with…Exploring brain mechanisms of identity attribution in presence hallucinations of Parkinsonian origin
Objective: Study cognitive, behavioral correlates of identity of presence hallucinations in Parkinson’s disease. Background: Presence hallucination (PH), the sensation that someone is nearby when no…Long-term dementia prevalence in Parkinson disease: Glass half-full?
Objective: To determine long-term, cumulative dementia prevalence rates in Parkinson disease (PD) using data from two large, ongoing, prospective observational studies. Background: Dementia is reported to occur in…
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