Trends in first line therapy for PD in Wales: A 16 year observational study
Objective: To examine the changes in first line therapy of newly diagnosed Parkinson’s patients between 2000 and 2016 in Wales. Background: There have been several…Lottery choice task as a detect tool for PD patients with pathological gambling
Objective: We aim to develop a tool lack of stigma to detect patients' impulse control problems. Background: Dopaminergic medication is current major treatment for Parkinson's…Validation of a One-Page Impulse Control Disorder Questionnaire in a Parkinson’s Disease Clinic
Objective: We seek to report data on ICD symptoms collected on 120 patients with Parkinsonism attending specialist movement disorder outpatient clinics using a newly devised,…Rotigotine protects dopaminergic neurons by targeting serotonin 1A receptors on astrocytes
Objective: In this study, we examined neuroprotective effects of rotigotine and involvement of serotonin 1A (5-HT1A) receptors on astrocytes in neuroprotective action of the drug…Dissociate effect of dopaminergic therapy in reward expectation and prediction error in PD patients with comorbid impulse control disorder
Objective: To study EEG oscillatory activity associated to reward prediction error in Parkinson’s disease (PD) patients with impulse control disorders (ICD) and determine how dopaminergic…Emulating the natural timing of dopamine receptor activation in Parkinson’s Disease
Objective: To emulate physiological dopamine receptor activation, in order to restore temporal patterns of dopamine-like signalling and normalise function in the striatum in Parkinson's disease.…GASTROPARK: Multicenter study on the efficacy of dopamine agonists for gastrointestinal symptoms in Parkinson’s disease
Objective: Main: To assess the modification of gastrointestinal symptoms in patients with Parkinson's disease before and after the introduction of dopamine agonists. Secondary: (1) To…Effectiveness of Rotigotine plus Intensive and Goal-based Rehabilitation versus Rotigotine alone in “de-novo” Parkinsonian subjects: A Randomized Controlled Trial with 18-month Follow-up
Objective: To evaluate the synergism between Dopamine Replacement Therapy (DRT) and rehabilitation in treating Parkinson's disease (PD), by investigating the short and the long-term effectiveness…On Converting Patients From Oral Dopamine Agonists to the Carbidopa/Levodopa Enteral Suspension Method – Real World Conversion Ratios
Objective: To review guidelines for initiating Carbidopa/Levodopa Enteral Suspension method of delivery in the treatment of Parkinson’s Disease (PD) and to compare guidelines with real…Effect of dopamine agonists versus levodopa as initial treatment in Parkinson’s Disease
Objective: We evaluated the efficacy of different starting drugs in the treatment of Parkinson's disease (PD), in order to further explore the initial therapy of…
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