Comparing motor and neuropathological features of Parkinson’s disease dementia and dementia with Lewy bodies
Objective: To compare motor and neuropathological features of Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) and to determine clinical and neuropathological differences…Pharmacological effect of adenosine A2A receptor antagonist for levodopa-induced dyskinesia associated with cellular energy homeostasis
Objective: To evaluate the Levodopa induced dyskinesia (LID) in the clinical view point of autophagy and cellular energy homeostasis, and the pharmacological effect of adenosine…Genetic polymorphism (rs6971) in translocator protein (TSPO) and its clinical relevance in Parkinson’s disease
Objective: The objective of this study will be to identify specific clinical patterns in Parkinson’s disease patients with respect to TSPO genetic polymorphism (rs69711). Background:…Factors associated with dyskinesia in Parkinson’s disease in Mainland China
Objective: To identify the association between dyskinesia and related risk factors, the medication dosage range considered safe and treatment-related variables.To identify the association between dyskinesia…Dorsolateral striatal neuronal activity in a rat model of Parkinson`s disease with levodopa-induced dyskinesias
Objective: This study aimed to investigate the firing properties of fast spiking interneurons (FSIs) and medium spiny neurons (MSNs) of the dorsomedial striatum (DLStr) and…Efficacy of opicapone in Parkinson’s disease patients according to baseline presence of dyskinesia: a post-hoc analysis from combined BIPARK-I and II
Objective: To evaluate the efficacy of opicapone (OPC) in levodopa-treated Parkinson’s Disease (PD) patients with or without baseline presence of dyskinesia (BPDys). Background: OPC, a…Hyperkinetic Movement Disorders in Congenital Disorders of Glycosylation
Objective: The aim of the current study was to investigate hyperkinetic movement disorders in patients affected by Congenital Disorders of Glycosylation (CDG) and to characterize…Clinical features of constipation in patients with Parkinson’s disease: a cross-sectional study in China
Objective: This study was designed to explore the clinical features of constipation, and investigate the risk factors of constipation in Chinese PD patients. Background: Constipation…Co-administration of levodopa and zonisamide reduces the serotonin transporter expression in a rat model of Parkinson’s disease
Objective: To investigate the change of striatal serotonergic system according to the administration of levodopa and zonisamide (ZNS) on the striatal serotonergic system, we analyzed the…Assessing the validity and reliability of MANAGE-PD tool to identify patients with Parkinson’s disease inadequately controlled on oral medications – Results from an international survey of general neurologists and movement disorder specialists
Objective: To evaluate the validity and reliability of MANAGE-PD tool. Background: Timely identification of advancing symptoms in patients with Parkinson’s Disease (PD), thereby improving opportunities…
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