- Abnormal Subthalamic Oscillations as Potential Biomarkers for Identifying the Dyskinesia-Inducing Region within the Subthalamic Nucleus in Parkinson’s DiseaseObjective: To investigate the characteristics of local field potentials (LFPs) associated with the STN region that elicit stimulation-induced dyskinesia (SID) in PD patients. Background: Approximately 50%…
- Prevalence of Helicobacter Pylori Infection Among Nepalese Parkinson’s Disease Patients and their Clinical ManifestationsObjective: To know the prevalence of Helicobacter Pylori infection among Nepalese Parkinson´s Disease patients and understand their clinical characteristics Background: Helicobacter pylori (HP) is prevalent…
- Efficacy and Safety of Amantadine in Parkinson’s Disease with Dyskinesia and Motor Fluctuations: A Systematic Review and Meta-AnalysisObjective: To evaluate the efficacy and safety of oral amantadine (AMA) compared to placebo in the treatment of dyskinesia (DYS) and motor fluctuations (MF) in…
- Altered EEG Theta Activity Characterizes Parkinson’s disease with Levodopa-induced DyskinesiaObjective: We explored the relationship between the build-up and the downscaling process in patients with Parkinson’s disease by analyzing theta frequency spectral bands. Background: During…
- Acute dystonic dyskinesias in a patient used fluvoxamine. Case reportObjective: To represent a case of acute dystonic dyskinesias after fluvoxamine use by the patient with obsessive thoughts and movements. Background: In psychiatric clinical practice,…
- Pharmacokinetic-Pharmacodynamic Modeling of Amantadine Extended-Release Capsule Effects on Dyskinesia in Parkinson DiseaseObjective: Evaluate pharmacokinetic/pharmacodynamic (PK/PD) relationships for the delayed- and extended-release (DR/ER) capsule formulation of amantadine [1] in the treatment of levodopa-related dyskinesia in Parkinson disease.…
- Genetic Variants and Levodopa Response in Parkinson’s Disease: Insights from MAO-B and DAT1 PolymorphismsObjective: This study aimed to find the association of genetic variations between Parkinson’s disease (PD) patients with and without levodopa-induced dyskinesia (LID). we intended to…
- Validation of the Kazakh Version of the Movement Disorder Society-Unified Dyskinesia Rating Scale.Objective: This study aimed to validate the Kazakh version of the Movement Disorder Society-Unified Dyskinesia Rating Scale Background: The Unified Dyskinesia Rating Scale (UDysRS) has…
- Buspirone/zolmitriptan combination exerts synergistic reduction in dyskinesia without worsening Parkinson disease motor symptomatologyObjective: Levodopa-induced dyskinesias (LID) may be amenable to interventions with striatal serotonergic receptors. Preclinical evidence suggests that co-administration of serotonergic agonists with selective receptor properties…
- Triple threat: A rare case of a patient with 3 co-existent autoimmune antibodies causing autonomic and movement disorderObjective: We describe a unique case of a patient with a constellation of movement and autonomic abnormalities. Serum paraneoplastic/autoimmune testing was positive for 3 separate…
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