Finger tapping-related brain activation and impact of cerebellar theta-burst stimulation in cervical dystonia patients
Objective: To assess brain activation during simple movements of the right hand in patients with cervical dystonia (CD) by means of fMRI. To test the…Verb naming in hypokinetic and hyperkinetic movement disorders: Preliminary results
Objective: To investigate verb naming differences in hypokinetic (Parkinson's disease, PD) and hyperkinetic (primary cervical dystonia, PCD) movement disorders; and to determine whether different effects…Neck proprioception is impaired in patients with idiopathic cervical dystonia
Objective: To investigate whether proprioceptive information generated from the neck is impaired in patients with idiopathic Cervical Dystonia (CD). Background: CD is a focal dystonia…Structural and functional brain network alterations in psychogenic dystonia
Objective: The aim of this study is to explore the brain structural and functional MRI abnormalities in psychogenic dystonia patients (pDYT). Background: Psychogenic movement disorders…Single unit activity of globus pallidus during voluntary movements in patients with cervical dystonia
Objective: To reveal the electrophysiological mechanism of voluntary movements with and without neck muscle exertion in patients with cervical dystonia. Background: Globus pallidus, as part…In-vivo free-water imaging and functional connectivity in a knock-in mouse model of DYT1 dystonia
Objective: To examine in-vivo functional connectivity and free-water diffusion imaging in dystonic mutant Tor1a knock-in (DYT1) and wild-type (WT) control mice. We test the hypothesis…Functional characterization of the upstream start codon in the GCH1 gene
Objective: To examine (1) the -22C > T point mutation which introduces a premature start codon upstream of the normal open reading frame (ORF) of…Refined basal ganglia model accounting for GPi modulation of thalamic tonic and burst modes
Objective: To test our hypothesis that a principal role of GPi GABAergic output is to regulate the dual burst and tonic modes of thalamocortical neurons.…Differences in processing proprioceptive input from the neck muscles may explain the benefit from sensory tricks in patients with idiopathic cervical dystonia
Objective: We used a paradigm of neck vibration to test the hypothesis that the sensory trick (ST), which is used by some patients with idiopathic…Heterozygous TUBB4A knock-out impairs mitochondrial motility in human neuronal model of DYT4
Objective: To study the role of tubulin beta 4A (TUBB4A) in mitochondrial motility in isogenic induced pluripotent stem cells (iPSC)-derived neurons. Background: Heterozygous mutations in…
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