Writer’s Cramp Dystonia during increasingly complex motor task: analysis of behavior and task fMRI
Objective: To evaluate the relationship between clinical features of dystonia and striatal BOLD activity. Background: Dystonia is a brain disorder which causes involuntary twisting movements, abnormal…A novel phasic and restricted basal ganglia thalamocortical subcircuitry model
Objective: To advance a novel basal ganglia thalamocortical (BGTC) model that accounts for GPi as a tonic-burst mode regulator of the thalamus and for restricted…Smell and Taste in Blepharospasm
Objective: To contribute to the better understanding of blepharospasm, we systematically assess olfactory and gustatory ability in subjects with blepharospasm, compared to subjects with cervical…PKAN is associated with significant peripheral metabolic alterations in the Dominican Republic cohort
Objective: Applying segmental bioimpedance testing to assess peripheral metabolic alterations in PKAN. Background: PKAN is a rare autosomal recessive disorder with >50 different mutations in…Exploring the pathophysiology of acquired dystonia by the use of high frequency somatosensory stimulation
Objective: To explore the effect of high-frequency repetitive sensory stimulation (HF-RSS) on the excitability of the sensorimotor cortex in acquired dystonia Background: Dystonia is currently…Tremor-dominant cervical dystonia and the cerebellum: lessons from saccade adaptation
Objective: To evaluate the role of the cerebellum in tremor-dominant cervical dystonia (CD) using a standardized saccade adaptation task. Background: While basal ganglia has long…Altered perceptual hand maps in focal hand dystonia
Objective: To assess implicit hand maps in patients with focal hand dystonia (FHD). Background: In FHD, changes in the perception of tactile stimuli are suggested…Intact organization of tactile space in isolated focal dystonia
Objective: To assess the organization of tactile space in patients with focal dystonia. Background: Changes in cortical sensorimotor organization have been previously demonstrated in isolated…An aberrant embouchure dystonia network predicts objective and functional measures of severity
Objective: To investigate functional brain networks underlying focal embouchure dystonia (FED) using resting-state functional connectivity (FC) magnetic resonance imaging and to correlate abnormal connectivity with…Regional, Not Global, Functional Connectivity Contributes to Isolated Focal Dystonia
Objective: To test the hypothesis that there is shared regional or global functional connectivity dysfunction in a large cohort with isolated focal dystonia affecting different…
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