Improving drug discovery using brain oscillations as biomarkers of Parkinson’s disease
Objective: The aim of this study was to assess the use of cortical oscillations as translational biomarkers for drug development for the motor symptoms of…Zolpidem ameliorates the freezing of gait in a patient with PAGF (pure akinesia with freezing of gait)-the possible neural mechanism
Objective: To investigate the possible mechanism of amelioration of freezing of gait (FOG) in a patient with PAGF (Pure Akinesia with Freezing of Gait) by…Bi-hemispheric phase synchronization in patients with Parkinson’s disease during stance, gait and upper limb motor tasks
Objective: To begin exploring if and how bi-hemispheric cortical phase synchronization (PS), as reflected by electroencephalography (EEG), during free overground walking, is associated with gait…Identification of a new biomarker in a mouse model of essential tremor using EEG
Objective: The aim of this work was to study the effect of harmaline-induced tremor on cortical oscillatory activities, and the sensitivity of potential EEG signatures…Towards a responsive deep brain stimulation for the treatment of essential tremor
Objective: To identify neurophysiologic markers of intention tremor in the ventral intermediate thalamic nucleus (Vim) and hand motor cortex to develop closed-loop deep brain stimulation…Neurophysiological evidence of posterior-cortical alterations in premanifest Huntington’s: An event-related brain potentials study of face and face-like objects processing
Objective: To investigate the behavioral and neurophysiological correlates of face and face-like-object recognition in premanifest Huntington's disease (preHD). Background: PreHD provide an excellent framework to…Inferring the causal interplay of motor related brain areas in the aging brain: A dynamic causal modeling (DCM) approach
Objective: To investigate the causal interplay of brain areas during the performance of a complex bimanual motor task in young and elderly subjects. Background: Coordination…TMS-EEG markers of inhibitory deficits in Huntington’s disease
Objective: Given the GABAergic nature of TMS-evoked EEG activity, we tested whether GABAergic deficits in Huntington's disease (HD) patients produce any significant change in TMS-EEG…Predictive performance of EEG theta spectral power over developing dementia in Parkinson’s disease
Objective: To investigate whether changes in EEG power spectra could predict development of dementia in Parkinson's disease (PD-D). Background: Different research groups have reported, that…Inferring the coupling of motor related brain areas during paced finger tapping in Parkinson’s patients
Objective: To analyze the coupling and causal interplay of motor related brain areas in Parkinson's patients during the performance of externally and internally paced finger…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.