Abnormal fractional anisotropy of the tremor network in tremor dominant Parkinson’s disease and Essential tremor plus syndrome
Objective: To evaluate alterations in fractional anisotropy (FA) of the basal ganglia-thalamocortical (BGTC) and cerebello-thalamocortical (CTC) network in tremor dominant Parkinson’s disease (TDPD) and essential…Validation of fully automated tremor analysis on common videos based on Computer Vision.
Objective: This project aims towards the development and validation of a fully automated framework for tremor analysis using common video recordings. Background: Till date, sensor-based…Diagnosed and Drug-Treated Prevalence of Essential Tremor in Pediatric Patients: Retrospective Analyses of Two US Healthcare Claims Databases
Objective: Estimate the prevalence of diagnosed and drug-treated essential tremor (ET) in the pediatric population using 2 US healthcare claims databases. Background: An ET diagnosis…Prevalence of sleep disorders symptoms in essential tremor
Objective: The aim is to study the prevalence of sleep disorders symptoms in patients with essential tremor (ET). Background: ET is the most common movement…Benefits and Risks of Staged Bilateral versus Unilateral VIM DBS for Essential Tremor
Objective: To compare the benefits and risks of staged bilateral versus unilateral VIM DBS using the largest ET DBS clinical trial dataset available to date.…Cortical and cerebellar excitability in essential tremor
Objective: To investigate the functional state of motor cortex excitability and the involvement of the cerebello-thalamo-cortical pathway using transcranial magnetic stimulation (TMS) in patients with…Using fMRI-based multivariate pattern analysis to differentiate between hyperkinetic movement disorders
Objective: We aimed to investigate differences in functional magnetic resonance imaging (fMRI) brain responses across hyperkinetic movement disorders (HMDs) during a bilateral finger-tapping task.We aimed…Preclinical Characterization of Suvecaltamide for Essential Tremor
Objective: To characterize the in vitro T-type calcium (CaV3) channel target pharmacology and in vivo anti-tremor profile of suvecaltamide (JZP385, CX-8998). Background: CaV3 channels, a…Comparison between clinical and kinematic assessment of bradykinesia
Objective: To compare the clinical and kinematic assessment of bradykinesia (movement slowness). Background: Bradykinesia may be present not only in Parkinson’s disease (PD), but also…Network detection and connectivity analysis to predict DBS-induced ataxia in essential tremor
Objective: We aim to differentiate networks associated with deep brain stimulation (DBS) induced ataxia in essential tremor (ET) patients and test if connectivity to these…
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