Neural mechanisms underlying step initiation failure in patients with Parkinson’s disease and freezing of gait
Objective: To investigate the neural mechanisms underlying gait initiation failure in Parkinson's disease patients with Freezing of Gait. Background: Freezing of Gait (FOG) is a…In-vivo free-water imaging and functional connectivity in a knock-in mouse model of DYT1 dystonia
Objective: To examine in-vivo functional connectivity and free-water diffusion imaging in dystonic mutant Tor1a knock-in (DYT1) and wild-type (WT) control mice. We test the hypothesis…Altered resting-state functional interhemispheric connectivity in Parkinson’s disease
Objective: To examine direct interhemispheric functional connectivity (FCi) in Parkinson's disease (PD) during resting-state fMRI and to investigate the relations between observed connectivity changes and…Finger tapping-related brain activation and impact of cerebellar theta-burst stimulation in cervical dystonia patients
Objective: To assess brain activation during simple movements of the right hand in patients with cervical dystonia (CD) by means of fMRI. To test the…MRI signatures of the brain of Parkinson’s disease and idiopathic REM sleep behavioral disorder subjects
Objective: To characterize brain microstructural integrity, iron loads, and functional connectivity in 10 idiopathic rapid eye movement sleep behavior disorder (RBD), 10 Parkinson's disease (PD)…Predicting therapeutic effects of atomoxetine and citalopram on response inhibition in Parkinson’s disease
Objective: (1) To reassess the behavioral impact of novel noradrenergic (atomoxetine) and serotonergic (citalopram) therapies for impulsivity and (2) to develop predictive models to identify…Functional deficits during response inhibition improve after dopaminergic medication for Parkinson
Objective: To study the neural correlates of impulse control in Parkinson's disease (PD) patients before and after the start of dopamine replacement therapy (follow up…Neural plasticity and freezing of gait: Stepping through the FoG
Objective: 1) To determine the efficacy of our cognitively challenging Agility Boot Camp (ABC-C) rehabilitation intervention and 2) to evaluate neural mechanisms and plasticity within…Depression, anxiety, and apathy in Parkinson’s disease: Insights from neuroimaging studies
Objective: (1) To evaluate the existing neuroimaging studies of depression, anxiety and apathy in Parkinson's disease (PD) and (2) to determine the key neural pathway…Brain mechanisms underlying visual processing in Parkinson’s disease
Objective: We used fMRI and a visual cognitive task to study brain mechanisms underlying visual processing at different cognitive loads in patients with PD and…
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