Early gastrointestinal dysfunction is predictive of faster progression in Parkinson’s disease
Objective: To evaluate whether constipation at time of diagnosis has prognostic significance in terms of motor and cognitive progression in PD. Background: There is evidence…Smooth muscle dysfunction in the gastrointestinal system in the 6-OHDA model of Parkinson´s Disease
Objective: To explore the connection between the central dopamine system and the autonomous nervous system in GI dysfunction in PD, using animal models. Background: Gastrointestinal…Gastrointestinal Symptoms and Enteric Nerve Dysfunction in A53T Mice
Objective: To investigate the relationship between α synucleinopathy-induced enteric neuropathy and gastrointestinal dysfunction in A53T mice. Background: Approximately 80-90% of PD patients suffer from GI…Gut microbiota geography in Parkinson’s disease in the world
Objective: The 16 rRNA analysis and the shotgun metagenome analysis in our cohort were compared with 5 previous reports by others. Background: In PD patients,…Unveiling the function of altered gut microbiota composition in Parkinson’s disease
Objective: To investigate the gut microbiome and metabolome in Parkinson’s disease (PD). Background: Recent evidence revealed that gut microbes promote alpha-synuclein pathology and motor deficits…A novel cause for unpredictable response to levodopa
Objective: [To describe a novel cause for unpredictable response to levodopa] Background: A fluctuating response to levodopa is common in advanced Parkinson’s disease and can…Helicobacter pylori eradication and risk of Parkinson’s disease in patients with peptic ulcers
Objective: To observe the effect of Helicobacter pylori eradication on the incidence of Parkinson's disease Background: The prevalence of Helicobacter pylori (H. pylori) is high in Parkinson's disease (PD)…Two-year prospective study reveals that gut dysbiosis predicts progression of Parkinson’s disease
Objective: This study is to examine whether intestinal microbiota correlate with pathology progress of PD severity and change of gut microbiota for 2 years. Background:…Gastroesophageal dysmotility in advanced Parkinson’s Disease
Objective: The aim of this study is to evaluate the patterns of gastroparesis in PD patients with motor fluctuations and dyskinesias. Background: Gastrointestinal dysfunction is…Probiotic correction of intestinal dysbiosis in Parkinson’s disease
Objective: To reveal the effect of probiotic on the content and condition of intestinal microbiota in Parkinson's disease (PD). Background: Constipation is an important non-motor…
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