Globus pallidus as a neurosurgical target in the management of levodopa-induced dyskinesias
Objective: Parkinson's disease (PD) is a neurodegenerative disorder characterized by the development of motor symptoms, as well as some non-motor changes. Symptomatic treatment of PD…Contribution of external globus pallidus to motor deficits of Parkinson’s disease: optogenetic studies in murine model
Objective: The present study explored whether altered activity of external globus pallidus (GPe) neurons contributes to the development of motor deficits of Parkinson’s disease (PD).…Bilateral Globus Pallidus interna Deep Brain Stimulation for the treatment of chorea-acanthocytosis: A case report from South Africa
Objective: We report on the efficacy of bilateral Globus pallidus interna deep brain stimulation as a treatment for Chorea-acanthocytosis (ChAc). Background: ChAc is an autosomal…Pallidal deep brain stimulation alters reward learning in segmental dystonia: a pilot study
Objective: To investigate the effect of pallidal deep brain stimulation (DBS) on reward learning in segmental dystonia. Background: Reversal learning is impaired in patients with…Pallidal single unit activity in cervical dystonia patients with unilateral deep brain stimulation
Objective: The aim of the current study is to characterize the neuronal activity of the pallidal area which gives the best benefit following unilateral deep…Unilateral Subthalamic Versus Unilateral Pallidal Stimulation in Parkinson’s Disease: A Randomized Double-Blind Crossover Study
Objective: To compare the acute effects of deep brain stimulation (DBS) of unilateral subthalamic nucleus (STN) and unilateral globus pallidus interna (GPi) on motor function…Pallidal deep brain stimulation entrains finely tuned gamma oscillations in motor cortex
Objective: Determine whether therapeutic pallidal deep brain stimulation can entrain finely tuned gamma oscillations in the motor cortex. Background: In Parkinson’s disease (PD), finely tuned…Movement vigor is differentially encoded in motor cortex and globus pallidus in Parkinson disease
Objective: To test the hypothesis that pallidocortical local field potential (LFP) beta oscillations encode movement vigor. Background: Recent work suggests the motor basal ganglia adjusts…Retrospective Review of Globus Pallidus Deep Brain Stimulation Electrode Contact Locations and Clinical Outcomes in Parkinson’s Disease
Objective: To evaluate the location of therapeutic electrode contacts and correlate those with the clinical outcomes of deep brain stimulation (DBS) of the globus pallidus…The role of genetics in patient selection and outcomes of deep brain stimulation in Parkinson’s disease
Objective: Determine the role of genetic factors in selecting candidates for, and evaluating outcomes of, deep-brain stimulation (DBS) within the framework of the multi-national Genetic…
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