Fatigue at different stages of parkinson’s disease
Objective: study fatigue as a key non-motor symptom of parkinson's disease Background: Fatigue in PD refers to a state of fatigue, lack of energy, a…Deep behavioural analysis of zebrafish models of Parkinson’s disease
Objective: The objective is to characterise parkinsonian phenotypes in genetic and pharmacological models of Parkinson's disease (PD) using zebrafish. Background: Parkinson’s disease (PD) is a…Clinically interpretable severity estimation of facial expression impairment in Parkinson’s disease
Objective: To develop a scalable and interpretable computer-vision based algorithm to measure the severity of facial impairment in Parkinson’s disease. Background: Neurological disorders frequently manifest…Neuroinflammation and Anti-Psychotic Drugs Induced Hyperkinesia or Dystonia in Treatment of Organic Brain Psychoses and Schizophrenia
Objective: Our study goal was evaluation of neuroinflammatory processes in patients with psychoses received anti-psychotic medications and developed hyperkinesia or dystonia symptoms. Evaluation of pro-inflammatory…Comparative score on the MDS-UPDRS scale I, II and IV in patients with Parkinson disease with and without cardiovascular risk factors.
Objective: To find any relationship between cardiovascular risk factors such as diabetes mellitus, hypertension or both and worse state in patient with PD measured with…Accelerometry to optimize optical flow measurement of repetitive finger tapping movements: A pilot study
Objective: To optimize optical flow (OF) measurement of repetitive finger tapping movements with the use of concomitant accelerometry in healthy volunteers. Background: Repetitive finger tapping…A novel phasic and restricted basal ganglia thalamocortical subcircuitry model
Objective: To advance a novel basal ganglia thalamocortical (BGTC) model that accounts for GPi as a tonic-burst mode regulator of the thalamus and for restricted…Severity of Motor Symptoms in Parkinson’s Disease in Kazakhstan (on the example of the city of Almaty)
Objective: Determine the severity of motor symptoms with Parkinson's disease using the MDS-UPDRS scale. Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by…Involuntary movements with abnormal brain imaging: A Case Report
Objective: To present a case of juvenile-onset Huntington's disease (HD) with a mixed phenotype and abnormal brain imaging. Background: HD is an autosomal-dominant neurodegenerative disorder…Objective quantifiable assessment of nocturnal movements in patients with Parkinson’s disease using a wearable sensor
Objective: We aimed to explore the relationship between impaired bed mobility, disease severity, and other factors putatively related to NH. Background: Nocturnal hypokinesia (NH) is…