Axial impairment and bradykinesia are related to increased CSF sTREM2, a neuroinflammation biomarker, in Parkinson’s disease
Objective: To explore the association between Parkinson’s disease (PD) motor symptoms and CSF biomarkers for neuroinflammation and neurodegeneration. Background: Previous in vivo and post mortem…Evaluation of neuroprotective role of carvacrol via Nrf2-NLRP3 axis in rotenone induced PD mice model
Objective: To explore the antioxidant and anti-inflammatory role of Carvacrol via Nrf2-NLRP3 axis in rotenone induced PD mice model Background: NLRP3 inflammasome mediated neuroinflammation is…RNA editing contributes to the inflammatory astrocytic response in Parkinson’s disease.
Objective: 1) Using an IPSC derived cell model to explore astrocytic responses alone and cocultured neurons to alpha-synuclein oligomer (αsynO) treatment.2) Determine the extent to…Movement disorders with phosphodiesterase 10A IgG autoimmunity
Objective: To report four new cases of phosphodiesterase 10A (PDE10A) IgG neurological autoimmunity. Background: PDE10A IgG was recently identified as a biomarker of paraneoplastic neurological…IMPACT OF COVID 19 ON PARKINSON’S DISEASE: A CROSS SECTIONAL STUDY
Objective: To review the impact of Covid 19 on symptoms and signs of Parkinsons as well as general being in patients with Parkinson’s Disease at…Characterising Natural Killer cells in early Parkinson’s disease
Objective: To determine whether the number and phenotype of Natural Killer (NK) cells in the blood is altered in early Parkinson’s disease (PD). Background: Accumulating…Mortality in Parkinson’s patients following Covid19 infection in the second wave of the pandemic
Objective: To analyze causes of mortality and death certification in Parkinson’s disease patients who had SARS- CoV2 in Reading, West Berkshire, United Kingdom (UK) Background:…Can treatment of Helicobacter pylori decrease Parkinson’s disease risk?
Objective: The aim of this study was to investigate the association between Helicobacter pylori (H. pylori) infection and the risk of Parkinson’s disease (PD). Background:…Inflammatory changes in subjects with de novo Parkinson’s disease
Objective: To examine whether inflammation is present in subjects newly diagnosed with Parkinson’s disease (PD). Background: Evidence for the role of inflammation in PD has…Blood microRNA-7 as a Progression Biomarker in Parkinson’s disease
Objective: This study investigates the use of microRNA-7-5p (miR-7-5p) as a potential biomarker for Parkinson’s disease (PD) progression. Background: MiR-7-5 is a microRNA that regulates…
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