Humor processing is affected by Parkinson’s disease and levodopa
Objective: This study investigated humor comprehension and appreciation deficits in Parkinson’s disease (PD) as potential non-motor symptoms, and the effect of levodopa on these processes.…Overview of the population of patients with advanced Parkinson’s disease (aPD) initiating therapy with levodopa-carbidopa intestinal gel (LCIG): POMPE-PARK study on French health insurance data (2013-2017)
Objective: To quantify the number of French aPD patients initiating continuous delivery of LCIG from 2013 to 2017 and to describe their demographic, clinical and…LY-487,379 enhances the anti-parkinsonian action of a low dose of L-DOPA in the MPTP-lesioned marmoset
Objective: To investigate the effect of selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulation on the anti-parkinsonian action of a low dose of…Comparison of gastrointestinal transit times in typical and erratic levodopa-responders in patients with Parkinson’s disease.
Objective: To determine if altered transit time in the various segments of the gastrointestinal (GI) tract relates to the variability of clinical responses and serum…Orthostatic hypotension in early onset Parkinson’s disease
Objective: To investigate Orthostatic hypotension (OH) feature in early onset Parkinson's disease (EOPD) , especially delayed OH and acute OH post drug. To explore OH…Motor subtype change between OFF and ON periods in patients with Parkinson’s disease
Objective: To identify if there is any difference in the motor subtype of PwPD between "off" stage and "on" stage. Background: Patients with Parkinson’s disease…12-month therapeutic evaluation of l-dopa carbidopa ascorbic acid solution (LCAS) in a cohort of Advanced Parkinson’s disease in a North-Indian tertiary care hospital
Objective: To prescribe LCAS to Parkinson’s disease(PD) patients whose symptoms were not adequately controlled on tablet l-dopa and compare the UPDRS-(I,II,III,IV) ON & OFF on…Sensorimotor inhibition relates to gait dysfunction in people with Parkinson’s disease
Objective: To determine how sensorimotor inhibition relates to objective measures of gait OFF and ON levodopa and how having Parkinson’s disease (PD) affects this relationship.…Claims Data Analysis of Parkinson’s Disease Medication Utilization
Objective: Characterize prominent medication utilization patterns among patients with Parkinson’s disease (PD). Background: Multiple classes of medications, as monotherapy or polytherapy, are prescribed to treat…Pill burden reduction in patients with advanced Parkinson’s disease: Comparative effectiveness of carbidopa/levodopa enteral suspension and Deep brain stimulation
Objective: To compare the real-world impact of initiating carbidopa/levodopa enteral suspension (CLES) or deep brain stimulation (DBS) on reducing pill burden (i.e. total number of…
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