Evolution of anti-parkinsonian drug prescribing patterns in Parkinson’s disease
Objective: To compare Parkinson’s disease (PD) treatment practices by movement disorder (MD) specialists across a decade, and to determine the factors that influence drug choice…Effect of Levodopa on gut microbiome in Parkinson’s Disease (PD)
Objective: To characterize changes in the gut microbiome in de novo PD subjects before and after initiating carbidopa/levodopa Background: The gastrointestinal microbiome in patients with…Sustained release triple drug loaded Microbaloons for management of Parkinson’s Disease
Objective: It is hypothesized that a drug delivery system that provides controlled and sustained release of PD drugs would afford better management of PD. Hollow…Grey matter atrophy in Parkinson’s disease with long-duration response
Objective: Aim of the study is to investigate neuroanatomical correlates of Long-Duration Response using structural magnetic resonance imaging (MRI) and voxel-based morphometry analysis. Background: Parkinson…Transcranial Photobiomodulation as an adjunct to Levodopa therapy in patients with Parkinson’s Disease; an open label pilot study
Objective: To explore the effects of transcranial Photobiomodulation (tPBM) on symptoms of Parkinson's Disease and establish this therapy's efficacy as an adjunct to Levodopa. Background:…Risk Thresholds of Levodopa Dose for Dyskinesia in Chinese Patients with Parkinson’s Disease: A Pilot Study
Objective: The objective of this study was to investigate the thresholds of levodopa dose to reduce the risk for dyskinesia in a Chinese PD population.…Safinamide ameliorates motor deficits and plastic alterations before the onset of L-DOPA-induced dyskinesia in a rat model of Parkinson’s disease
Objective: To investigate the effects of safinamide (saf) on synaptic plasticity of spiny projection neurons (SPNs) and the antiparkinsonian effect in dopamine (DA) denervated rats…Neuropathy in patients treated with LCIG in the Czech and the Slovak Republic
Objective: To identify occurrence, severity and clinical factors associated with neuropathy in patients with Parkinson's disease (PD) treated with LCIG (levodopa – carbidopa intestinal gel)…Cortical gamma oscillations as biomarkers for levodopa-induced dyskinesia
Objective: The aim of our study was to characterize cortical neuronal network activity in levodopa-induced dyskinesia in order to better understand the underlying pathophysiology and…Relative Preservation of Serotonergic Function Increases Response to Treatment in Early PD
Objective: To investigate interactions between the serotonergic and dopaminergic systems in early PD as related to (i) response to treatment and (ii) dopamine (DA) release,…
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