MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Levodopa(L-dopa)"

  • 2019 International Congress

    Cortical gamma oscillations as biomarkers for levodopa-induced dyskinesia

    C. Güttler, J. Altschüler, K. Tanev, S. Böckmann, JK. Haumesser, A. Kühn, C. van Riesen (Berlin, Germany)

    Objective: The aim of our study was to characterize cortical neuronal network activity in levodopa-induced dyskinesia in order to better understand the underlying pathophysiology and…
  • 2019 International Congress

    Relative Preservation of Serotonergic Function Increases Response to Treatment in Early PD

    J. Fu, M. Matarazzo, I. Klyuzhin, K. Cheng, C. Bevington, J. Mckenzie, N. Heffernan, E. Shahinfard, M. Mckeown, AJ. Stoessl, V. Sossi (Vancouver, BC, Canada)

    Objective: To investigate interactions between the serotonergic and dopaminergic systems in early PD as related to (i) response to treatment and (ii) dopamine (DA) release,…
  • 2019 International Congress

    DBS for PD in Albania

    I. Zekja, R. Alimehmeti, F. Dashi, S. Grabova, M. Petrela, M. Rralacolli, J. Kruja (Tirana, Albania)

    Objective: DBS: surgical procedure of choice for PD. Albanian experience. Background: Parkinson disease (PD) : the decrease of dopamine’s levels because of nigro – striatal…
  • 2019 International Congress

    Biphasic Dyskinesias in Parkinson’s disease Patients treated with Levodopa/Carbidopa Intestinal Gel: Insights from a Multicenter Retrospective Analysis

    M. Marano, T. Naranian, L. Di Biase, A. Di Santo, R. Arca, G. Cossu, P. Marano, V. Di Lazzaro, A. Fasano (Rome, Italy)

    Objective: We aimed to characterize Parkinson's disease (PD) patients who developed the onset of new troublesome dyskinesias after Levodopa-Carbidopa Intestinal Gel (LCIG) initiation. We were…
  • 2019 International Congress

    Safinamide reduces membrane excitability and synaptic transmission of striatal spiny projection neurons in a rat model of Parkinson’s disease

    A. Tozzi, M. Sciaccaluga, P. Mazzocchetti, G. Bastioli, V. Ghiglieri, B. Picconi, C. Caccia, C. Keywood, G. Padoani, P. Calabresi (Perugia, Italy)

    Objective: The effect of safinamide (saf) on the electrical membrane properties and both excitatory and inhibitory synaptic transmission of striatal spiny projection neurons (SPNs) was…
  • 2019 International Congress

    Availability of levodopa and clinicopathological features of patients with multiple system atrophy

    C. Ishida, K. Komai, K. Takahashi, Y. Motozaki, A. Tagami, S. Shibata, M. Asakawa (Kanazawa, Japan)

    Objective: To investigate the availability of levodopa for pathologically confirmed multiple system atrophy (MSA) patients and determine the clinicopathological features of levodopa responders with MSA.…
  • 2019 International Congress

    Continuous levodopa- carbidopa gel recovers motor cortex plasticity in advanced Parkinson’s disease

    K. Kolmancic, N. Prezelj, N. Kriznar Zupancic, M. Trost, D. Flisar, M. Gregoric Kramberger, R. Rajnar, Z. Pirtosek, M. Kojovic (Ljubljana, Slovenia)

    Objective: The objective of this study was to investigate if continuous infusion of levodopa- carbidopa gel (LCIG) improves motor complications of Parkinson's disease (PD) and…
  • 2019 International Congress

    Opposing effects of levodopa on basal ganglia activity in Parkinson’s disease during motion and rest

    R. Jech, S. Holiga, F. Růžička, H. Möller, J. Roth, M. Schroeter, E. Růžička, K. Mueller (Prague, Czech Republic)

    Objective: To explore the pattern of activation within the motor network during the movement and resting phases of the tapping task in Parkinson’s disease (PD)…
  • 2019 International Congress

    Gastrointestinal symptoms as a risk factor for the appearance of motor fluctuations in patients with advanced Parkinson disease

    C. Borrue-Fernandez, M. Boimorto (San Sebastian Reyes, Spain)

    Objective: Gastrointestinal alterations in patients with Parkinson`s Disease (EP) provoke alterations in the absorption of levodopa that facilitates the development of motor fluctuations. Study the…
  • 2019 International Congress

    Impact of repeated oral administration of Opicapone on the plasma pharmacokinetics of levodopa

    M. Nomoto, A. Takeda, K. Iwai, A. Nishimura, N. Hattori (Ehime, Japan)

    Objective: To examine the inhibitory effect of COMT on the plasma pharmacokinetics of levodopa resulting from repeated, once daily, oral administration of an Opicapone (OPC)…
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